ID A0A1I2F280_9ACTN Unreviewed; 374 AA.
AC A0A1I2F280;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:SFE98766.1};
GN ORFNames=SAMN05216251_10795 {ECO:0000313|EMBL:SFE98766.1};
OS Actinacidiphila alni.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=380248 {ECO:0000313|EMBL:SFE98766.1, ECO:0000313|Proteomes:UP000199323};
RN [1] {ECO:0000313|EMBL:SFE98766.1, ECO:0000313|Proteomes:UP000199323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3510 {ECO:0000313|EMBL:SFE98766.1,
RC ECO:0000313|Proteomes:UP000199323};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FONG01000007; SFE98766.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2F280; -.
DR STRING; 380248.SAMN05216251_10795; -.
DR Proteomes; UP000199323; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06292; PBP1_AglR_RafR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000199323};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..69
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 346..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 39009 MW; E1EF6B57A5D53F1E CRC64;
MVAFRPLASG AVTARLADIA AQAGVSEATV SRVLNGKPGV SATTRESVLA ALDLLGYERP
VRLRQRSAGL VGLITPELEN PIFPAFAQII GQALTRQGYT PVLATQTPGG STEDELVEML
VERGVAGIIF VSGLHADSTA DMERYTRLQG QGVPFVLING FSEKVNAPFV SPDDRGAVRL
AVTHLAALGH RRIGLAVGQK RFVPVQRKIE GFVASMADVL GRTEEQAQEL VQHSLFTLEG
GQAAATALIA SGCTAIVCAS DMMALGAIRA ARQQGLSVPD DVSVVGFDDS PLIAFTDPPL
TTIRQPVAAM SQAAVNALLE EIGGTPAPHS EFVFLPELVV RGSTAAAPAV RSTPVPPQQP
SSGVTRGTPD PTEV
//
