ID A0A1I2FYM1_9BACT Unreviewed; 720 AA.
AC A0A1I2FYM1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Bacteriocin-processing peptidase. Cysteine peptidase. MEROPS family C39 {ECO:0000313|EMBL:SFF09511.1};
GN ORFNames=SAMN05444380_1384 {ECO:0000313|EMBL:SFF09511.1};
OS Thermophagus xiamenensis.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC Thermophagus.
OX NCBI_TaxID=385682 {ECO:0000313|EMBL:SFF09511.1, ECO:0000313|Proteomes:UP000181976};
RN [1] {ECO:0000313|EMBL:SFF09511.1, ECO:0000313|Proteomes:UP000181976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19012 {ECO:0000313|EMBL:SFF09511.1,
RC ECO:0000313|Proteomes:UP000181976};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FONA01000038; SFF09511.1; -; Genomic_DNA.
DR RefSeq; WP_044138553.1; NZ_FONA01000038.1.
DR AlphaFoldDB; A0A1I2FYM1; -.
DR STRING; 385682.SAMN05444380_1384; -.
DR eggNOG; COG2274; Bacteria.
DR InParanoid; A0A1I2FYM1; -.
DR OrthoDB; 9760358at2; -.
DR Proteomes; UP000181976; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043214; F:ABC-type bacteriocin transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd18570; ABC_6TM_PCAT1_LagD_like; 1.
DR CDD; cd02418; Peptidase_C39B; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005897; Pept_C39_ABC_bacteriocin.
DR InterPro; IPR005074; Peptidase_C39.
DR InterPro; IPR039421; Type_1_exporter.
DR NCBIfam; TIGR01193; bacteriocin_ABC; 1.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF03412; Peptidase_C39; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50990; PEPTIDASE_C39; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000181976};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 160..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..131
FT /note="Peptidase C39"
FT /evidence="ECO:0000259|PROSITE:PS50990"
FT DOMAIN 162..443
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 476..711
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 720 AA; 80679 MW; 501C5D6DFC96FFED CRC64;
MSVKIKQRDI TDCGAACLAS VAAHYKLKLP VSRIRQMAET DKKGTNMLGL LKASEKMGFT
AKGVKGGVDA LPKIPLPAIA HVVVNRVLHH YVVIYKVKDD RVEYMDPGDG QMHKITVSEF
AEIWTGVLLL MVPGEDFTQA NEKVSNLRRF VFLLKPHKSI LIQALLGAVI YTILGLSTSV
YIQKITDNVL VYGNTNLLNV LSIGMVVLLI FQIFIGASKS VLMLRTGQKI DAQLILGYYK
HLLKLPQRFF DTMRVGEIIS RINDAVKIRV FINDTAVSLI VNVFIVIFSF SLMFIYSWKL
ALIMALVIPL YSVVYYLVNY LNRKRERKLM ENAADLESQL VESLNSVKTI KQFGLEDFAN
IKTETRFITL LKTVYKSGIN SVFAGNSSEF LNRAFIIILL WTGSYFVIDQ SITPGELLSF
YAILGYFTSP AAQLVGVNKT IQNALIASDR LFEIMDLERE ADDDKIELRE DLIGDIRFAN
IKFSYGTRVD VFDNFSLLIP KGKLTAIIGE SGSGKTTLAS LLQKLYPLTD GSIYIGDHNI
NYFTNQSLRR LVASVPQKLD LFAGNVIENI AVGEFHPDME RILTICRQLG ILDFIEKLPA
GFETYLGENG ASVSGGQKQR LAIARALYKN PEILLLDEAT SSLDPESESY VQKAIDQLKS
EGKTIIVIAH RLSTVMEADK IVVLGNGRLI EEGTHFDLYK KHGKYFQMWQ KQMPPVLSEF
//
