ID A0A1I2G2Z7_9MICO Unreviewed; 1257 AA.
AC A0A1I2G2Z7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Ribonuclease E {ECO:0000313|EMBL:SFF11493.1};
GN ORFNames=SAMN04488035_1673 {ECO:0000313|EMBL:SFF11493.1};
OS Flavimobilis marinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Jonesiaceae;
OC Flavimobilis.
OX NCBI_TaxID=285351 {ECO:0000313|EMBL:SFF11493.1, ECO:0000313|Proteomes:UP000198520};
RN [1] {ECO:0000313|Proteomes:UP000198520}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19083 {ECO:0000313|Proteomes:UP000198520};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; FONZ01000002; SFF11493.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2G2Z7; -.
DR STRING; 285351.SAMN04488035_1673; -.
DR Proteomes; UP000198520; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000198520};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 641..724
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1010..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1079..1110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1126..1257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..104
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..422
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..447
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..505
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..524
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1034..1049
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1257 AA; 131735 MW; 42C6959C1817C6E2 CRC64;
MNSDSTTASD NAAQPVKKVR RRVVRTAGTP AAADTAAVTP AAEPLTTSAP QSSDRPTLDV
MAELASTAPP QRQRSATRPA KAPEALDIEL PERTAAERPP RKRAPRPAKG SAAPEQSADQ
STGAQASDAQ ASTEQSAPSV TEQQEPTTAP AAKRPSRSRR ATKPAGEGVA AEAAAPEQAA
PEQASAPEQA ADAEPAPERA PRQRRSRAKA TNADQLTLEA AAADAETPAE APAADDAPQG
RRRGRASAKA APDAAPEADA AAQPEAAERP ARSRRSRGSR GAGAPEAAAT DEAPAQTSEL
AATDPTTTTN ADDEAPAERR PSRSRGGRSR KAAGPASDTD TTDATTDAAA EAPAEDAAEA
AQSRPASGAV LFQAPETTPR RTRRRVSAAA GPPEALVPAL VETAADEDAE LEENEDDNLD
PDVEHTDASA ADGNDSADED DSDNDNDDEQ GSAPRRRRRR GGRGRRSRSQ SDSSGDSQDD
VDDAEDDGNV RRNGRNDRAE RNDDSADEDT DASDNAEGAD NGEDDDEGSS RRRRRRRRGS
RSESDAPRAS SSGRTRAPSD EVTALKGSTR LEAKRQRRRE GRDAGRRRSI ITEAEFLARR
ESVERSMVVR EADGRTQIAV LEDGVLVEHY VSQQEQASMA GNVYLGRVQN VLPSMEAAFI
DVGKGRNAVL YAGEVNWDAA GLEGQPRRIE QALKSGDSVL VQVTKDPIGH KGARLTSQIT
LAGRYLVYVP GGGMTGISRK LPDTERSRLK KILRELVPDT AGVIVRTAAE GASEDELRAD
IARLQGQWEK IEKKAKTASA PALLQGEPDL AIRVVRDIFN DDFSSLVISG DSAWDEISGY
VGQLAPDLAE RVTKWTGTND VFAEHRVDEQ LAKGMDRKVW LPSGGSLVID RTEAMTVVDV
NTGKFTGSGG TLEETVTRNN IEAAEEIVRQ LRLRDIGGII VIDFIDMVLE SNRDLVLRRL
VECLGRDRTK HQVAEVTSLG LVQMTRKRVG QGLVEAFSST CEHCNGRGFI VHTEPNERPA
GNGGGQQQSA PKAGGDEKRS RRKRGGAKDE VPANVPVVPV LPEAREAVKA TLATIAAAAA
HAHEHDEHPA AATPSAESVA EASEAGAADP KNSALVIDVL AELKRHEEEK AESADAAPEA
QGAPAEAAPA EAAPEAEPKK APRRSTRAAG SRGRTTRAAG TTAAPAEVPV PAADAPTSDA
PAAAGQEAGD AGAGAEAAQA ARFPADTSGS AESGSAGSAG AGASEPVVEA GASNPQD
//
