ID   A0A1I2G3P7_9ACTN        Unreviewed;       938 AA.
AC   A0A1I2G3P7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=DNA-binding transcriptional activator of the SARP family {ECO:0000313|EMBL:SFF11753.1};
GN   ORFNames=SAMN05421541_106163 {ECO:0000313|EMBL:SFF11753.1};
OS   Actinoplanes philippinensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=35752 {ECO:0000313|EMBL:SFF11753.1, ECO:0000313|Proteomes:UP000199645};
RN   [1] {ECO:0000313|EMBL:SFF11753.1, ECO:0000313|Proteomes:UP000199645}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43019 {ECO:0000313|EMBL:SFF11753.1,
RC   ECO:0000313|Proteomes:UP000199645};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC       {ECO:0000256|ARBA:ARBA00005820}.
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DR   EMBL; FONV01000006; SFF11753.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2G3P7; -.
DR   STRING; 35752.SAMN05421541_106163; -.
DR   OrthoDB; 7628974at2; -.
DR   Proteomes; UP000199645; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd15831; BTAD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR   PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000199645}.
FT   DOMAIN          1..98
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51755"
FT   DNA_BIND        1..98
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ   SEQUENCE   938 AA;  102522 MW;  911C847ADD4F1BA9 CRC64;
     MLNVRVLGPI TADIDGRPVD LGRRHQRAIV GILVAARGDT VSADRLIEEL WNGRPPARAT
     VSLQVYVSNL RRALEPARAS RGPATTLVRR SSGYALSLPE NAVDAWRFEQ SLAQARSLPA
     DQARPLLLDI LRWWRGPVFG ESRDQTWAIA EASRLDELRL LAREQAIQAA LRIGDPATAM
     LEAQQLVRDE PLRTEACRLA ALTLWAVGRE SDALETLRHH RDAVRDEFGL DPTPALSVLE
     QAILNQRTEV LHAETEPDRI RPAQLPLQLA AFTGRDAELA ELTALAQASA ATVPVAVITG
     MGGVGKTALA LRWAHQHQDE YPDGQLYIDL LGFAPAGEPL PAAEALRSFL TSLGVPYDAV
     PVSVPDRAAL LRSMLSGRRM LFVLDNARDA DQVRDLIPGS AGCAVLITSR ALLNDLITMH
     HAHPVSLSAF VAEDAGRYLT RRVGAARTTA EPDAVGEIVA VCGGLPLALA VVAARIATNP
     TFTLAAIAKE LRGSGGLDGF AAPGVTRDPR SVFSWSYRHL PAEAAALFRH LALHPGPDVT
     VATAASLTGA APATVRTWMN HLVEAHLIRE HRPGRFRFHD LLRAYAAELA GSDDDDAART
     AVVRRGLDHY LHSAMAATAL LLPQRYPITV LPPAPGVRPE AVTTEAEALD WFDSEYRNLL
     AALAVAEEND DGPYCWQFNW AIAHYVQDRR ARLDDSITHL RRALALAESH QDDWWITTLT
     LNLARSYYRF DQRGESRAWY ERGVELARGS GDRFRLTQAL LGMAGVINGE HRVPTREAAE
     TAHPYAREAL EICRELPLDN GRVLNEAVAL GHIAWYESHQ PDGYRAAVGH FATIVDTLLR
     IDYRIGAAGT LLEWGHLSQH AGATGDAIAA YHRSLELAGE VRELQAEALT GLVYCHRDLG
     DDTGADEFRQ AALAIIEHRR HPGMQRIRAT LEAASRPD
//