ID   A0A1I2G9F8_9BACT        Unreviewed;       815 AA.
AC   A0A1I2G9F8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=TonB-dependent Receptor Plug Domain {ECO:0000313|EMBL:SFF13838.1};
GN   ORFNames=SAMN04488541_101736 {ECO:0000313|EMBL:SFF13838.1};
OS   Thermoflexibacter ruber.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Thermoflexibacteraceae;
OC   Thermoflexibacter.
OX   NCBI_TaxID=1003 {ECO:0000313|EMBL:SFF13838.1, ECO:0000313|Proteomes:UP000199513};
RN   [1] {ECO:0000313|EMBL:SFF13838.1, ECO:0000313|Proteomes:UP000199513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GEY, DSM 9560 {ECO:0000313|Proteomes:UP000199513};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane
CC       {ECO:0000256|ARBA:ARBA00004571}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004571}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC       {ECO:0000256|RuleBase:RU003357}.
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DR   EMBL; FONY01000017; SFF13838.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2G9F8; -.
DR   STRING; 1003.SAMN04488541_101736; -.
DR   OrthoDB; 9804995at2; -.
DR   Proteomes; UP000199513; Unassembled WGS sequence.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.1120; Carboxypeptidase-like, regulatory domain; 1.
DR   Gene3D; 2.40.170.20; TonB-dependent receptor, beta-barrel domain; 1.
DR   Gene3D; 2.170.130.10; TonB-dependent receptor, plug domain; 1.
DR   InterPro; IPR008969; CarboxyPept-like_regulatory.
DR   InterPro; IPR012910; Plug_dom.
DR   InterPro; IPR037066; Plug_dom_sf.
DR   InterPro; IPR039426; TonB-dep_rcpt-like.
DR   InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR   InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR   PANTHER; PTHR30069; TONB-DEPENDENT OUTER MEMBRANE RECEPTOR; 1.
DR   PANTHER; PTHR30069:SF29; VITAMIN B12 TRANSPORTER BTUB; 1.
DR   Pfam; PF13715; CarbopepD_reg_2; 1.
DR   Pfam; PF07715; Plug; 1.
DR   Pfam; PF00593; TonB_dep_Rec; 1.
DR   SUPFAM; SSF49464; Carboxypeptidase regulatory domain-like; 1.
DR   SUPFAM; SSF56935; Porins; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003357};
KW   Receptor {ECO:0000313|EMBL:SFF13838.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199513};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   TonB box {ECO:0000256|ARBA:ARBA00023077, ECO:0000256|RuleBase:RU003357};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..815
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011538030"
FT   DOMAIN          129..234
FT                   /note="TonB-dependent receptor plug"
FT                   /evidence="ECO:0000259|Pfam:PF07715"
FT   DOMAIN          345..755
FT                   /note="TonB-dependent receptor-like beta-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF00593"
SQ   SEQUENCE   815 AA;  90949 MW;  111604ED350D7F6E CRC64;
     MKKFLFFSIL SFFYLPLSFA QNVGIIRGTV KDKNTQEALI GVTVLIEGTQ IGTTTDADGN
     YKLDKVPVGS YNLRASFVGY KTLTKFNINL TSGNAQIINF ELEEEVSTLK EVEITATQSK
     SASVADIITP LSTQSLTTEE IRSNPGGNFD ISRVVQVLPG VGGTSGSVGG FRNDIVIRGG
     APNENVYYLD GIEIPVINHF TTQGSAGGPT GILNVSFIED VKLSSSAFDA RYDNALASTF
     QFKQREGNPD RFSGNIRLSS TELATTFEGP ISPKTTYLAS VRRSYLQLLF QAIDLPIRPN
     YWDFQYKITH KINAKTSITA LGVGAIDEFT FAIPRQSSPE KEYILRSVPS INQWNYTVGF
     ALKRLVNNGY INIALSRNTF DNQLDRFEDK DEGNESKRIL KARSQETENK LRIDVNKFVN
     GWKFSYGLVA QYVQFNNDVF NRIRKEIRDA QGQLLQPQIA VNFNTDIDFF RYGAFGQVSK
     SLLNNKLGLS LGLRTDMNSF TETGNNPLET LSPRLSLSYA LADKWNLNAS VGTYYKTPIY
     TILSYRNEQG ELVNKDAKYT NSTHYVGGLE FLPKDDLRFT VEGFYKSYRN YPVSVRDGIS
     LANQGGDFGA IGNEEVTTNG IGNAYGFEFY AQQKLTKNIF AVFSYTFVRS QFAGLDGKLV
     PSAWDNRHLI SALFGKKFNK GWEIGMRYRF AGGAPLTPFD LVASQKNYPT LGVGILDFSK
     LNSERLTAFN QFDFRIDKKW NFRRATFDLY LDVQNALGFQ TPAFPQYTFQ RTADNSAFAT
     TDGNPLRTDG ANGIPLILSN NEATVLPSLG FIIEF
//