ID A0A1I2GXD9_9ACTN Unreviewed; 340 AA.
AC A0A1I2GXD9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=MerR HTH family regulatory protein {ECO:0000313|EMBL:SFF22395.1};
GN ORFNames=SAMN05216574_11049 {ECO:0000313|EMBL:SFF22395.1};
OS Blastococcus sp. DSM 46838.
OC Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC Geodermatophilaceae; Blastococcus.
OX NCBI_TaxID=1798228 {ECO:0000313|EMBL:SFF22395.1, ECO:0000313|Proteomes:UP000198589};
RN [1] {ECO:0000313|Proteomes:UP000198589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 46838 {ECO:0000313|Proteomes:UP000198589};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the beta sliding clamp family.
CC {ECO:0000256|ARBA:ARBA00010752}.
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DR EMBL; FOND01000010; SFF22395.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2GXD9; -.
DR STRING; 1798228.SAMN05216574_11049; -.
DR Proteomes; UP000198589; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00140; beta_clamp; 1.
DR CDD; cd01107; HTH_BmrR; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.10.150.10; DNA Polymerase III, subunit A, domain 2; 2.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR046938; DNA_clamp_sf.
DR InterPro; IPR001001; DNA_polIII_beta.
DR InterPro; IPR022637; DNA_polIII_beta_cen.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR PANTHER; PTHR30478:SF0; BETA SLIDING CLAMP; 1.
DR PANTHER; PTHR30478; DNA POLYMERASE III SUBUNIT BETA; 1.
DR Pfam; PF02767; DNA_pol3_beta_2; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SMART; SM00480; POL3Bc; 1.
DR SUPFAM; SSF55979; DNA clamp; 2.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000198589};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 8..75
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 340 AA; 36181 MW; 6A9A88432F48687A CRC64;
MEERVRGIGR MARETGLTVS ALRFYDGAGI LVPARVDPHS GYRWYGDDQV APARLVARLR
RVGLPLADIR RVLEHRRDPA VVDEILGAHL VRLEDGLADA RRELSAARAL LDLELPVPTV
LRTTTTELAA ALRAVRYAVG ADPGLPMLTG VLLDVDDDAV RLAATDRYRL AVATLPDASV
TGPACSALLP VDLADEVLAA LGTDGSVTVA VDGPVITVEL PGGTVRGRRL DHDFPDYRRI
LRPSSAHRID TDAAELRAAL EAAPTRTVPH GPDGAEQTAS VLSLGEVEIG VNREFLLEAL
DAGAAGQLVL ELDGPITPLA LRDPARPGNV SMLMPVRLPA
//
