ID   A0A1I2GXS1_9ACTN        Unreviewed;       678 AA.
AC   A0A1I2GXS1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=DNA helicase IV {ECO:0000313|EMBL:SFF21879.1};
GN   ORFNames=SAMN05216574_11032 {ECO:0000313|EMBL:SFF21879.1};
OS   Blastococcus sp. DSM 46838.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Blastococcus.
OX   NCBI_TaxID=1798228 {ECO:0000313|EMBL:SFF21879.1, ECO:0000313|Proteomes:UP000198589};
RN   [1] {ECO:0000313|Proteomes:UP000198589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 46838 {ECO:0000313|Proteomes:UP000198589};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOND01000010; SFF21879.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2GXS1; -.
DR   STRING; 1798228.SAMN05216574_11032; -.
DR   Proteomes; UP000198589; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF13245; AAA_19; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000198589}.
FT   DOMAIN          169..521
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         190..197
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   678 AA;  72700 MW;  C5599B7284E0BA3A CRC64;
     MSPPAEPDTA EPVLTAERAH LARAAECLAQ MRTAASAAVD AGVDAWASER LGAARAERLR
     ALAADPGVPP FFGRIDRSRE SFHIGRRHVR DAVGDPVVID WRAPMSRPFY QATAADPQGL
     VRRRRFGFAD GQLTGYEDEL LGAGQEGGEF LRQEIERPRS GPMRDIVATV QPDQDDIVRA
     PLTDSICVQG APGTGKTAVG LHRAAYLLYT HGGQLARTGV LVVGPNRAFL RYIEQVLPTL
     GEVDVEQTTV ADLTARVPVR AEDGPEAAVL KGDARMAEVL RRALWGEIRK PADSVQVPLA
     GRRYRVPVER LKRYVDDVRR RARADDDQQM LHYVAGRERL MLLVAEDARR QSEEAAGTPT
     DAETHRAARS AEVRAFCDEV WPVRDAAGLL GDLWRDPVRL ARAARGILDD GEMALLHWPV
     PPRSVRSAPW TAADAVLADE LAGLLERTPG YGHVVVDEAQ DLSPMQCRAV ARRLAAGSLT
     VLGDLAQATS PWSPADWRDT LAALGRPDTV IRPLTRGYRV PGEVLDLANR LLPLIAPDLS
     PATAVRADPG SLRVRRVTDP DGAVVQVVAE LSEAPGSVGI ICADAAVDDV ATALAGAGLP
     AAVLADDGAE VTRIAVVPAG LAHGLEFDAV VVVEPAAIVA AEPRGLHRLY VVLTRAVSTL
     VVLHREDLPA PLADLPAP
//