ID   A0A1I2H0G2_9ACTN        Unreviewed;       353 AA.
AC   A0A1I2H0G2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Threonine aldolase {ECO:0000313|EMBL:SFF22893.1};
GN   ORFNames=SAMN05216574_11065 {ECO:0000313|EMBL:SFF22893.1};
OS   Blastococcus sp. DSM 46838.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Blastococcus.
OX   NCBI_TaxID=1798228 {ECO:0000313|EMBL:SFF22893.1, ECO:0000313|Proteomes:UP000198589};
RN   [1] {ECO:0000313|Proteomes:UP000198589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 46838 {ECO:0000313|Proteomes:UP000198589};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the threonine aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006966}.
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DR   EMBL; FOND01000010; SFF22893.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2H0G2; -.
DR   STRING; 1798228.SAMN05216574_11065; -.
DR   Proteomes; UP000198589; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR   PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198589}.
FT   DOMAIN          33..283
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
SQ   SEQUENCE   353 AA;  37797 MW;  92E49D034B94F69C CRC64;
     MDTLRRACDR ALTGHGPQSA ADLLASIPAD TVTDRYGDGG VVAELEEEVA AVLGLPAAVY
     LPSGVMAQQS ALRVHADRRG RRTVVHHPEC HLERHEGRAL ERLQGLIGRP TGDRDRLLLR
     ADLEPVAEPP AALVVELPQR DLGGQLPPWD DLLAQVAWAR DRGAAAHLDG ARLWEAAAGY
     GRPPADVAAL FDTTYVSFYK ALGALPGCCL AGPVDVVAEV REWRKRMGGT LFGLWPGAAS
     ALSCLRRRLP LMAGYLERAR EIAATVRDLP GVTVVPDPPQ TPMLHLLLRT GADEFRAGAR
     ALAEGGLWTW ERPAATGDPA VQRVELAVGD ATMALTLPEI RDAVRSLAGG QRP
//