ID   A0A1I2HIN3_9ACTN        Unreviewed;       330 AA.
AC   A0A1I2HIN3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Zinc-type alcohol dehydrogenase-like protein {ECO:0000256|RuleBase:RU364000};
GN   ORFNames=SAMN05421541_108169 {ECO:0000313|EMBL:SFF28747.1};
OS   Actinoplanes philippinensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=35752 {ECO:0000313|EMBL:SFF28747.1, ECO:0000313|Proteomes:UP000199645};
RN   [1] {ECO:0000313|EMBL:SFF28747.1, ECO:0000313|Proteomes:UP000199645}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43019 {ECO:0000313|EMBL:SFF28747.1,
RC   ECO:0000313|Proteomes:UP000199645};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Quinone oxidoreductase subfamily.
CC       {ECO:0000256|RuleBase:RU364000}.
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DR   EMBL; FONV01000008; SFF28747.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2HIN3; -.
DR   STRING; 35752.SAMN05421541_108169; -.
DR   Proteomes; UP000199645; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08252; AL_MDR; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR014182; ADH_Zn_typ-1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   NCBIfam; TIGR02817; adh_fam_1; 1.
DR   PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU364000};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU364000};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199645};
KW   Zinc {ECO:0000256|RuleBase:RU364000}.
FT   DOMAIN          20..327
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   330 AA;  35189 MW;  F8892CDB8396CD94 CRC64;
     MTNTMKAVGY RKSLPVDHPE SLLDLTLPVP EPRPHDLLVR VEAVSVNPVD VKLRAGRDPH
     GEPAVLGWDA AGVVERTGDA VTLFQPGDEV FYAGSINRPG TNAQFHLVDE RLVGPKPSTL
     DFAAAAALPL TALTAWEALF NRLRLDDAST GTLLAVGAAG GVGSILVQLA RRLTGLTVIG
     SASRPASRDW VAAQGAHRVV DHHDGFAGLD DAVDHIVSPH SAGMIETYAR ILRPFGAIVA
     IDEPDGLELL PLKSKSIAWH WEFMFTRALH DAASSAQYDI LTEVARLVDK GVLKTTEARR
     LDGITAANLR TAHRIQESGG AIGKTVLAGF
//