ID   A0A1I2J907_9ACTN        Unreviewed;       530 AA.
AC   A0A1I2J907;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II {ECO:0000313|EMBL:SFF49406.1};
GN   ORFNames=SAMN05216574_11512 {ECO:0000313|EMBL:SFF49406.1};
OS   Blastococcus sp. DSM 46838.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Blastococcus.
OX   NCBI_TaxID=1798228 {ECO:0000313|EMBL:SFF49406.1, ECO:0000313|Proteomes:UP000198589};
RN   [1] {ECO:0000313|Proteomes:UP000198589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 46838 {ECO:0000313|Proteomes:UP000198589};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOND01000015; SFF49406.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2J907; -.
DR   STRING; 1798228.SAMN05216574_11512; -.
DR   OrthoDB; 9803968at2; -.
DR   Proteomes; UP000198589; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   CDD; cd05904; 4CL; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR   PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:SFF49406.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198589}.
FT   DOMAIN          25..394
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          445..521
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   530 AA;  56516 MW;  63D8C2ACA7E47DFE CRC64;
     MALASPYPDV EIPNLSVPEF VLAAGKERPD APALIDGLKG DVITHGQLAA YVDRVAANLH
     ARGLRKDDVV AVFCPNTPWF PVVFHGIAAA GCVMSPINSL YTPDEIAFQL KDSGAKVLIT
     ISLFLDRAKA AAEKSPVDEI VVLDGAEGHA NLFDLLGEDA PSVQVDIDPA NDLVTLPYSS
     GTTGLPKGVM LTHRNLVANV AQCRPLIDFG PDERIIAVLP FFHIYGLTVL MNQGLAWGGA
     VVTLPRFDLE DFLRTIQDQK ITRAFVAPPI LLAMAKHPLV DEYDLSSLTS ILSGAAPLDE
     QLALAAQNRL RKGADTGVSV AQGYGMTELS PVSHTTPDIG CEPPGAGQPP KGSVGYALPN
     TECRLIDPGT GQDAAAGERG ELWVRGPQVM KGYLNNAEAT AHTLDDDGWL HTGDVAIVDE
     TGAYTVVDRV KELIKYKGYQ VAPAELEAVL IGHDEIADAA VIGVPDKESG EELPKAFVVR
     APGSELTEEA VMEYMAVKVA PHKKVRFVEF IDAVPKSAAG KILRKDLKAR
//