ID A0A1I2J996_9CLOT Unreviewed; 329 AA.
AC A0A1I2J996;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Site-specific recombinase XerD {ECO:0000313|EMBL:SFF50570.1};
DE SubName: Full=Tyrosine recombinase XerC {ECO:0000313|EMBL:PWL53564.1};
GN ORFNames=DBY38_07475 {ECO:0000313|EMBL:PWL53564.1},
GN SAMN04487885_101204 {ECO:0000313|EMBL:SFF50570.1};
OS Clostridium cadaveris.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1529 {ECO:0000313|EMBL:SFF50570.1, ECO:0000313|Proteomes:UP000182135};
RN [1] {ECO:0000313|EMBL:SFF50570.1, ECO:0000313|Proteomes:UP000182135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NLAE-zl-G419 {ECO:0000313|EMBL:SFF50570.1,
RC ECO:0000313|Proteomes:UP000182135};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PWL53564.1, ECO:0000313|Proteomes:UP000246114}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIM:MAG 903 {ECO:0000313|EMBL:PWL53564.1};
RA Jeraldo P., Boardman L., White B.A., Nelson H., Goldenfeld N., Chia N.;
RT "The uncultured portion of the human microbiome is neutrally assembled.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC the cutting and rejoining of the recombining DNA molecules.
CC {ECO:0000256|ARBA:ARBA00003283}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; QAMZ01000036; PWL53564.1; -; Genomic_DNA.
DR EMBL; FOOE01000001; SFF50570.1; -; Genomic_DNA.
DR RefSeq; WP_027638081.1; NZ_JAUDCX010000051.1.
DR AlphaFoldDB; A0A1I2J996; -.
DR STRING; 1529.SAMN04487885_101204; -.
DR eggNOG; COG4974; Bacteria.
DR OrthoDB; 283809at2; -.
DR Proteomes; UP000182135; Unassembled WGS sequence.
DR Proteomes; UP000246114; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30349:SF41; INTEGRASE_RECOMBINASE HI_1414-RELATED; 1.
DR PANTHER; PTHR30349; PHAGE INTEGRASE-RELATED; 1.
DR Pfam; PF02899; Phage_int_SAM_1; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000182135}.
FT DOMAIN 12..117
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 139..322
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 329 AA; 37767 MW; 6E74EF43845D52E2 CRC64;
MKYNIDDLKE INSLPQTLIE FLNYLDVIKG KSPNTIAAYK ADLIMFFRFI KIYKGLNEED
CEFEEIPIDD IGNKVIRSIK LSDLYAFLSF TEKYRNNGSY ARARKVATLK SFFKYLNGKS
KIIDENPATE LESPKISKRN PIYLTLSESQ TLLRSLDDTS KNYERDYCIL TLFLNCGLRV
SELCSIDVTK IKEDTLTIIG KGNKERTVYL NKACLKAISD YLAVRDGSKL PEAEKNSLFI
SNKNRQISVR SVERLVKKYT QEAGLTKNKY TPHKLRHTAA TLMYKHGNVD IRSLQQILGH
ENISTTQIYT HVDNETLREA VKSNPLSDE
//
