ID A0A1I2JN03_9ACTN Unreviewed; 296 AA.
AC A0A1I2JN03;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415};
GN ORFNames=SAMN05421541_112350 {ECO:0000313|EMBL:SFF54146.1};
OS Actinoplanes philippinensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=35752 {ECO:0000313|EMBL:SFF54146.1, ECO:0000313|Proteomes:UP000199645};
RN [1] {ECO:0000313|EMBL:SFF54146.1, ECO:0000313|Proteomes:UP000199645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43019 {ECO:0000313|EMBL:SFF54146.1,
RC ECO:0000313|Proteomes:UP000199645};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890}.
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DR EMBL; FONV01000012; SFF54146.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2JN03; -.
DR STRING; 35752.SAMN05421541_112350; -.
DR OrthoDB; 9803306at2; -.
DR Proteomes; UP000199645; Unassembled WGS sequence.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000313|EMBL:SFF54146.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199645};
KW Transferase {ECO:0000313|EMBL:SFF54146.1}.
FT DOMAIN 8..271
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 296 AA; 31747 MW; 6CF7B486352DC3CB CRC64;
MTTKRAVKAV IPAAGLATRF LPATKAVPKE LLPVVDRPVL QYIVEEAAAA GITDVLLVTG
RGKTAMVDHF DRRPDVEARL EEKGDQKRLA AVRRSSELAD IYTVRQGEAL GLGHAVGTAA
SHVGDNAFAV LLGDEFVEED KPLLPAMLDL QEKTGGIVLA FMEVAPHETS RYGIASVRTT
DDPDVVEVTG LVEKPSPEEA PSNLAVLGRY VLPGSIFDVI ADTKPGNGGE IQLTDAMATM
LADGVPVHGI VYRGHRYDTG MPLGYLQAVV QLAVQREDLG EEFRAWLTEF VGGWKG
//
