ID A0A1I2K7Z7_9MICO Unreviewed; 223 AA.
AC A0A1I2K7Z7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=adenosylhomocysteine nucleosidase {ECO:0000256|ARBA:ARBA00011974};
DE EC=3.2.2.9 {ECO:0000256|ARBA:ARBA00011974};
GN ORFNames=SAMN05216329_1759 {ECO:0000313|EMBL:SFF61201.1};
OS Curtobacterium sp. YR515.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Curtobacterium.
OX NCBI_TaxID=1855316 {ECO:0000313|EMBL:SFF61201.1, ECO:0000313|Proteomes:UP000199282};
RN [1] {ECO:0000313|EMBL:SFF61201.1, ECO:0000313|Proteomes:UP000199282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YR515 {ECO:0000313|EMBL:SFF61201.1,
RC ECO:0000313|Proteomes:UP000199282};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via salvage
CC pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-
CC thioadenosine (hydrolase route): step 1/2.
CC {ECO:0000256|ARBA:ARBA00004945}.
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DR EMBL; FOOD01000003; SFF61201.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2K7Z7; -.
DR UniPathway; UPA00904; UER00871.
DR Proteomes; UP000199282; Unassembled WGS sequence.
DR GO; GO:0008782; F:adenosylhomocysteine nucleosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008930; F:methylthioadenosine nucleosidase activity; IEA:InterPro.
DR GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; IEA:UniProtKB-UniPathway.
DR GO; GO:0009164; P:nucleoside catabolic process; IEA:InterPro.
DR CDD; cd09008; MTAN; 1.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR InterPro; IPR010049; MTA_SAH_Nsdase.
DR InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR NCBIfam; TIGR01704; MTA_SAH-Nsdase; 1.
DR PANTHER; PTHR46832; 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE; 1.
DR PANTHER; PTHR46832:SF1; 5'-METHYLTHIOADENOSINE_S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE; 1.
DR Pfam; PF01048; PNP_UDP_1; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167}.
FT DOMAIN 1..218
FT /note="Nucleoside phosphorylase"
FT /evidence="ECO:0000259|Pfam:PF01048"
SQ SEQUENCE 223 AA; 22962 MW; 363C4066E674AFBE CRC64;
MSEEVSAFAG LLGGVPILDG PVGGHDEHHL LDVGGATVAV RRSGIGFTNA TAAVAHAFHD
FGSGIPVISV GTAGGLMHGV EIGDVVVGDR YVNLNADATA FGYALGQVPG MPTGYEPDDR
LVEQALASDA GYRLRSATIG SSEIFVTEGR ARLLRTAFPA VAAVDMESAA IAQFAHVHAM
PFVSVRCISD LCAPDGDEFK EHLDDAAARA ARVVHDVVTG LVS
//
