ID A0A1I2KW44_9ACTN Unreviewed; 494 AA.
AC A0A1I2KW44;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Ricin-type beta-trefoil lectin domain-like {ECO:0000313|EMBL:SFF70568.1};
GN ORFNames=SAMN05421541_118157 {ECO:0000313|EMBL:SFF70568.1};
OS Actinoplanes philippinensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=35752 {ECO:0000313|EMBL:SFF70568.1, ECO:0000313|Proteomes:UP000199645};
RN [1] {ECO:0000313|EMBL:SFF70568.1, ECO:0000313|Proteomes:UP000199645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43019 {ECO:0000313|EMBL:SFF70568.1,
RC ECO:0000313|Proteomes:UP000199645};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FONV01000018; SFF70568.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2KW44; -.
DR STRING; 35752.SAMN05421541_118157; -.
DR OrthoDB; 5240321at2; -.
DR Proteomes; UP000199645; Unassembled WGS sequence.
DR GO; GO:0046556; F:alpha-L-arabinofuranosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0031221; P:arabinan metabolic process; IEA:InterPro.
DR GO; GO:0019566; P:arabinose metabolic process; IEA:InterPro.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR015289; A-L-arabinofuranosidase_B_cat.
DR InterPro; IPR038964; ABFB.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR39447; ALPHA-L-ARABINOFURANOSIDASE B; 1.
DR PANTHER; PTHR39447:SF2; ALPHA-L-ARABINOFURANOSIDASE B; 1.
DR Pfam; PF09206; ArabFuran-catal; 1.
DR Pfam; PF14200; RicinB_lectin_2; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR638964-3};
KW Lectin {ECO:0000313|EMBL:SFF70568.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199645};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..494
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039427944"
FT DOMAIN 38..346
FT /note="Alpha-L-arabinofuranosidase B catalytic"
FT /evidence="ECO:0000259|Pfam:PF09206"
FT DOMAIN 392..480
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|Pfam:PF14200"
FT ACT_SITE 234
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR638964-1"
FT ACT_SITE 310
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR638964-1"
FT DISULFID 39..49
FT /evidence="ECO:0000256|PIRSR:PIRSR638964-3"
FT DISULFID 99..104
FT /evidence="ECO:0000256|PIRSR:PIRSR638964-3"
FT DISULFID 190..191
FT /evidence="ECO:0000256|PIRSR:PIRSR638964-3"
SQ SEQUENCE 494 AA; 51021 MW; 6BF5E0E176951AD8 CRC64;
MGTRFSWRTA MAVAATAVLT ATALVTTGSA AGAAGTLPCD IYAGGGTPCV AAHSTTRALF
GAYSGSLYQV RRWSDGATTN VGVLSAGGYA NAATQDSFCS GTYCTIVRIY DQTSRHNDLT
IAPGGGANPT ADQGANAAAL PVTAGGRKVY GVYISAGNGY RNNATNGIAT GSQPEGMYMV
TEGTHVNDRC CFDYGNAETN NMDTGNGDMD AIYFGNLCWF SPCSAGPRVA ADLENGLFAG
GNGSWTANTG RNSAFVTAVL KNNGTSTYAI KDGNAQSGGL ATRYNGALPT QSGYNPMTKQ
GAIILGIGGD NSNGSVGSFF EGVMTSGYPS DATENAVQAN IVSVGYGKSV TFPVNGATYR
LTNLQSGKVL DATNCGTANG TTVQQWQSLG NTCQQWRFTS VGANKWTITN VNAGKVLDAV
NCGLALGTAV NLWQSLGNTC QQWAVIPAGN GRYELVVENS GMVLDDQDCG TANGTPARLW
MWLNNTCQLW SIAP
//
