ID A0A1I2LMU4_9EURY Unreviewed; 763 AA.
AC A0A1I2LMU4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN04488063_0328 {ECO:0000313|EMBL:SFF79868.1};
OS Halopelagius inordinatus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae.
OX NCBI_TaxID=553467 {ECO:0000313|EMBL:SFF79868.1, ECO:0000313|Proteomes:UP000198876};
RN [1] {ECO:0000313|Proteomes:UP000198876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7739 {ECO:0000313|Proteomes:UP000198876};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOOQ01000001; SFF79868.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2LMU4; -.
DR STRING; 553467.SAMN04488063_0328; -.
DR Proteomes; UP000198876; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198876}.
FT DOMAIN 429..488
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 565..763
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 763 AA; 82252 MW; B088F8B39FC7D151 CRC64;
MSERETVWFV TGEAVPDVDF GAGIELSASD GYPDRRRDCG VVVVTDPARV VETTAPTVCY
TDFDPEDVPD PGRFDAFVPR GETAMLETQV RWLLARGPRR EPSAAGTESS VSTIDERSRL
QRLYEGTTAL VAAETTSELF ARTLDIADEI LDFDNSTICV HEGDRFRVCA NVGTLELDHT
VPDDTGILGE TYWSGESVLV DDVREHPAAA PNDPDHRSVV SIPIGEFGVF QAFSTTVGSF
DLTDFHLAEL LVSYAAETAA RIESEETVRR GRERVEALHG GAVELAAVTD LEELFERAVA
VAEDVLAFDI CNIGVVDGDD ITPVAASSGV AEDGVQKLSL DDGSIAAKTH LTGETHVVTD
MAEDEDAEPA KSTYRSGLSV PIGDVAVFQA ASSLPDAFDE TDAELAELLM AHVAVTADRI
RAEDGLREER DRSTALFEQV SDAAVAYEID GASGTVRVRE VNRTFEETFG VEASEAVGRD
LTELVVPDGV TDAAELRVVD GESHRSEVRR CGPDGERDFI LNVVPFASGG RADEGFALYT
DITERKRREA ELERQNERLA EFTNIVSHDL RNPLSVARGH LELARETESE ESFEAVREAL
VRMETLIDDL LSLARQGAVV GDPEPVDLGE VACRAWQTVD APDATLSVPA TATVVADGDR
LDELLGNLFR NAVEHGATRE RESAVTVTVG PLASADGFYV EDDGPGIAPD RRDAVFEPGE
TTGGDGIGYG LPIVRRIAEA HDWSVTLCES ATGGARFEFT GTE
//
