ID A0A1I2MP01_9BACT Unreviewed; 310 AA.
AC A0A1I2MP01;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Lipid kinase, YegS/Rv2252/BmrU family {ECO:0000313|EMBL:SFF93172.1};
GN ORFNames=SAMN05216383_102165 {ECO:0000313|EMBL:SFF93172.1};
OS Prevotella sp. KH2C16.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=1855325 {ECO:0000313|EMBL:SFF93172.1, ECO:0000313|Proteomes:UP000198560};
RN [1] {ECO:0000313|Proteomes:UP000198560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH2C16 {ECO:0000313|Proteomes:UP000198560};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; FOOW01000002; SFF93172.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2MP01; -.
DR STRING; 1855325.SAMN05216383_102165; -.
DR OrthoDB; 9786026at2; -.
DR Proteomes; UP000198560; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR005218; Diacylglycerol/lipid_kinase.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR045540; YegS/DAGK_C.
DR NCBIfam; TIGR00147; YegS/Rv2252/BmrU family lipid kinase; 1.
DR PANTHER; PTHR12358:SF106; LIPID KINASE YEGS; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF19279; YegS_C; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SFF93172.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198560};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 170..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..139
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 310 AA; 35832 MW; 7210BF113B9D5B6C CRC64;
MAVNENKWGI LYCPKNSFRP QKRWENIEKV LRSERIDFDY VQSESTGSVE RLVKMMINNG
YRTLIIIGGD SALNDAVNCL MQTEKEVRDQ IALGVIPNGM MNDFAHFWGF QEGEIERSVK
WLKEHRVRKI DLGRINYKNK HGEPCHRYFL NCINIGLIAT IMNLRRQTRH IVGSRTVSYV
ISFILMIFQR LEYKMHLKIN GESINRKVMT VCVGNALGYG QTPNAVPYNG LLDVSVVYHP
EMAQLIEGIY LFVRGKFLNH KSVHPYRTKE VQVRNEEKAL VGIDGRLLNS PLGEYTIRVE
QEVINFLIPA
//
