ID A0A1I2N9Z7_9FIRM Unreviewed; 455 AA.
AC A0A1I2N9Z7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Putative efflux protein, MATE family {ECO:0000313|EMBL:SFF99930.1};
GN ORFNames=SAMN04487761_10142 {ECO:0000313|EMBL:SFF99930.1};
OS Lachnospiraceae bacterium C7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1792306 {ECO:0000313|EMBL:SFF99930.1, ECO:0000313|Proteomes:UP000198643};
RN [1] {ECO:0000313|EMBL:SFF99930.1, ECO:0000313|Proteomes:UP000198643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C7 {ECO:0000313|EMBL:SFF99930.1,
RC ECO:0000313|Proteomes:UP000198643};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOPE01000001; SFF99930.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2N9Z7; -.
DR STRING; 1792306.SAMN04487761_10142; -.
DR OrthoDB; 9776324at2; -.
DR Proteomes; UP000198643; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13138; MATE_yoeA_like; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43549; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR PANTHER; PTHR43549:SF2; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198643};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 455 AA; 49272 MW; EA15A2A4BA74487B CRC64;
MEVKNKNAIT TGVIWKQILI FFFPILIGAF FQTLYNTVDA AVVGKFAGTE ALASVGGSSG
QILNFVFSFF MGLATGATVI IAQHFGANEY EKVDDALHTA YTFGLVGGII LGIIGIIFVK
PLLNLLKTPS NLMDGSTIYV RILFAGLVFT LIYNMGAGIL RAIGDSKRPL YILIVCCGVN
IILDVIFVMV LKMGVTGAGI ATDISQALSA ILVTWLLMKK TVGMKLSIAK LHINIKTLNR
ILKIGLPTAI AGSMFSVSNM IVQTSLNQMG VNVVAAWTAY GRIDALWWMI NQAFSVSITT
FVGQNYGAGL PKRIRKAVAE VLAMEMGTGL ILAVVFIAFA PKLLGMFASS SEVIDIGVQI
SKLLPPFYAV FAISEILSAT LRAENYVMVA TVSNLLGICA FRIIWVEFIV PNAGMMQILK
CYPISWVLVS LLVLGYYIVM QPRILRGLHK QVQVS
//
