ID   A0A1I2P3Z8_9SPHN        Unreviewed;       455 AA.
AC   A0A1I2P3Z8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Fructuronate reductase {ECO:0000313|EMBL:SFG08181.1};
GN   ORFNames=SAMN05518801_10720 {ECO:0000313|EMBL:SFG08181.1};
OS   Novosphingobium sp. CF614.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=1884364 {ECO:0000313|EMBL:SFG08181.1, ECO:0000313|Proteomes:UP000199304};
RN   [1] {ECO:0000313|EMBL:SFG08181.1, ECO:0000313|Proteomes:UP000199304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CF614 {ECO:0000313|EMBL:SFG08181.1,
RC   ECO:0000313|Proteomes:UP000199304};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOOR01000007; SFG08181.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2P3Z8; -.
DR   STRING; 1884364.SAMN05518801_10720; -.
DR   OrthoDB; 271711at2; -.
DR   Proteomes; UP000199304; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR000669; Mannitol_DH.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR   PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199304}.
FT   DOMAIN          28..177
FT                   /note="Mannitol dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01232"
FT   DOMAIN          206..401
FT                   /note="Mannitol dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08125"
SQ   SEQUENCE   455 AA;  49268 MW;  A8D50BA2E6F1B227 CRC64;
     MRLSFASLAQ AGAGVQRCGY DRHGQRVGIV HFGIGAFHRA HQAWYTDLAM AAGERDWMIS
     GVSLRSPDVA EQMNPQDGLY TVMERSAAGV TLRIVGSVRE VLVARREPDA VVERMASADT
     RIVSFTVTEK GYCRAPDGSL DLTLAGEDSI YRFLRDGLAR RRDAGLPGLT LLSCDNLADN
     GQQLQRLVGE YLQSMDPELG EWVHVHCTFP ATMIDRIVPA TTDADRDAVA AELGQRDEAT
     VVTEPFSQWV IEDRFAGDRP RWEDVGAQLV SDVAPYEVAK LRMLNGAHSA LAYLGLGRGY
     TYVHEAVGDP VLGPMVERLM REEAATSFEA AAGQDLQAYA ANLLARFANP ALQHRLIQIA
     MDGSQKIPQR WLGTLAAQQR KGRSCPAILA ALAGWLRHAR GDNGPVDDPR AAEIKAIWEA
     AGVAGIVPAL FGPDGALSSI WTPTSEDTAA VIEGL
//