ID A0A1I2P8D6_9FIRM Unreviewed; 674 AA.
AC A0A1I2P8D6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Methyl-accepting chemotaxis sensory transducer with Cache sensor {ECO:0000313|EMBL:SFG12344.1};
GN ORFNames=SAMN04487761_1053 {ECO:0000313|EMBL:SFG12344.1};
OS Lachnospiraceae bacterium C7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1792306 {ECO:0000313|EMBL:SFG12344.1, ECO:0000313|Proteomes:UP000198643};
RN [1] {ECO:0000313|EMBL:SFG12344.1, ECO:0000313|Proteomes:UP000198643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C7 {ECO:0000313|EMBL:SFG12344.1,
RC ECO:0000313|Proteomes:UP000198643};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOPE01000005; SFG12344.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2P8D6; -.
DR STRING; 1792306.SAMN04487761_1053; -.
DR Proteomes; UP000198643; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198643};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 317..369
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 388..638
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 674 AA; 73177 MW; 1D7DF26864C498A3 CRC64;
MEGKIQNKDI KRFNKTISGK LLRRILPLII FSIAIVIIFL IFNARTIILS SAENGLKQET
ASNANSVGCD ISNFLGEANS MALTLENREF RDDDDLFSFL ENSKQFSTDA PNGIYLGLSN
GQLIDLSGWV PADDYVVTER SWYAEGLKHE TFTTGEPYLD LVTGKLVVPI SRAITLKDGR
DGVAAADFFL SSITEKTNAL KPMGKGSSLL LSDDMIIAYS NEKFSGTSVK DHSDDLLLTH
IYSKLQSNPS KVLKLEGNGK SFYVDYEKVP GTNWTLISYV DEDDVLADLN RFMIICSCAA
IIMIIIITIV MLFTMSSVVS KPVKNLTEVI IGITNKDFTI DIPDRNNDEI GEMNHNMRKF
ISNMHITLST MKEVSDQLSY EADTSKDESS TMYNEAKEQS DSMNMLKGTV EGMAQAVSEL
SNDATSLADK VGTLTAQGTE TNTVMKELVD IANQGKNDMR SVTENMDNIS KSMSDVNSAV
EHVDESAKQI NNIIEMINSI ASQTNLLSLN ASIEAARAGE AGKGFAVVAD EIGKLANDSA
DATTEIASII GDIAEQITSL AKKSTENVDA IKRSTESVET AEKTFEKIFT NLGVTGDTVQ
EMITDMNAVN EIATSLASIA EEQAASSEEI SASLDKLTSS AENVSSSSLK IKESSVGVSN
GADTINESVN TFKL
//
