ID A0A1I2Q3T0_9CLOT Unreviewed; 536 AA.
AC A0A1I2Q3T0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Prolyl-tRNA synthetase {ECO:0000313|EMBL:SFG20907.1};
GN ORFNames=DBY38_05355 {ECO:0000313|EMBL:PWL54090.1}, SAMN04487885_1349
GN {ECO:0000313|EMBL:SFG20907.1};
OS Clostridium cadaveris.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1529 {ECO:0000313|EMBL:SFG20907.1, ECO:0000313|Proteomes:UP000182135};
RN [1] {ECO:0000313|EMBL:SFG20907.1, ECO:0000313|Proteomes:UP000182135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NLAE-zl-G419 {ECO:0000313|EMBL:SFG20907.1,
RC ECO:0000313|Proteomes:UP000182135};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PWL54090.1, ECO:0000313|Proteomes:UP000246114}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIM:MAG 903 {ECO:0000313|EMBL:PWL54090.1};
RA Jeraldo P., Boardman L., White B.A., Nelson H., Goldenfeld N., Chia N.;
RT "The uncultured portion of the human microbiome is neutrally assembled.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QAMZ01000027; PWL54090.1; -; Genomic_DNA.
DR EMBL; FOOE01000034; SFG20907.1; -; Genomic_DNA.
DR RefSeq; WP_074846586.1; NZ_OBJM01000024.1.
DR AlphaFoldDB; A0A1I2Q3T0; -.
DR STRING; 1529.SAMN04487885_1349; -.
DR eggNOG; COG0442; Bacteria.
DR OrthoDB; 9809052at2; -.
DR Proteomes; UP000182135; Unassembled WGS sequence.
DR Proteomes; UP000246114; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR GO; GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR CDD; cd04334; ProRS-INS; 1.
DR CDD; cd00861; ProRS_anticodon_short; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR Gene3D; 3.90.960.10; YbaK/aminoacyl-tRNA synthetase-associated domain; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR044140; ProRS_anticodon_short.
DR InterPro; IPR036754; YbaK/aa-tRNA-synt-asso_dom_sf.
DR InterPro; IPR007214; YbaK/aa-tRNA-synth-assoc-dom.
DR PANTHER; PTHR42753; MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER; 1.
DR PANTHER; PTHR42753:SF2; PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF04073; tRNA_edit; 1.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF55826; YbaK/ProRS associated domain; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:SFG20907.1}; Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000256|ARBA:ARBA00023146, ECO:0000313|EMBL:SFG20907.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000182135}.
FT DOMAIN 243..358
FT /note="YbaK/aminoacyl-tRNA synthetase-associated"
FT /evidence="ECO:0000259|Pfam:PF04073"
FT DOMAIN 449..535
FT /note="Anticodon-binding"
FT /evidence="ECO:0000259|Pfam:PF03129"
SQ SEQUENCE 536 AA; 60648 MW; 6737D770C27CA1C3 CRC64;
MRMKNTLSCT LRNAPAEATK DIESYKLMLR AGIIRKEAPG VFNFLPLGMK VVNNIKKVIL
DTMEELNSEE IKSSYLSNAF INGFTTKDCY NNTYSLNRNY ISKLTGTFGE VLENTKNNVY
RFHEFTTDFE NIEKPKHGLL KCRENIIFQG FEIQGLESEE SKENPMKEEI IKDLENMGLD
VFTLKNCITN DLIIEDIVVS SDLGEDMLLQ CKSCETMEES EMFSIHPQIN QQDEVKDKNK
VLTPDIKTID DLVKFLDIKK ENIAKTLIYK AGKKTIAVMI PGNRDASEGK IKEFLKCFPI
IDMADEESVK FATGADIGFA GPIGIKADYL LVDEEVANMK NFVVGANDTN YHYINVNYGR
DFEGLIGDFK TAEGRDTCKE CDGELCSSSY IKIGSFITNK NIGIKGRSSV TVNEIKINIS
RVLGLIVENH SKENEIIWPE IICPYHVAII IALGKNEEQI KAGEDLYKRI RAIDKNVILD
DREDRVGAKF KDIELMGVPV RIVVGKYIKD GMVEYKDRNS DEPSIISLDE VVDRIN
//
