ID   A0A1I2R969_9CORY        Unreviewed;      1335 AA.
AC   A0A1I2R969;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:SFG34421.1};
GN   ORFNames=SAMN05660282_00583 {ECO:0000313|EMBL:SFG34421.1};
OS   Corynebacterium spheniscorum.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=185761 {ECO:0000313|EMBL:SFG34421.1, ECO:0000313|Proteomes:UP000199065};
RN   [1] {ECO:0000313|EMBL:SFG34421.1, ECO:0000313|Proteomes:UP000199065}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J11, PG 39 {ECO:0000313|Proteomes:UP000199065};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOPJ01000003; SFG34421.1; -; Genomic_DNA.
DR   STRING; 185761.SAMN05660282_00583; -.
DR   OrthoDB; 9805617at2; -.
DR   Proteomes; UP000199065; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd17989; DEXHc_HrpA; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:SFG34421.1};
KW   Hydrolase {ECO:0000313|EMBL:SFG34421.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199065}.
FT   DOMAIN          84..238
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          309..476
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   DOMAIN          1201..1335
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
SQ   SEQUENCE   1335 AA;  148369 MW;  1C93FE4CC106DB1B CRC64;
     MNNQHTEPRG LKRELYEALP TLTIADEHRF RRRLRRARNP KALAAIAQDL KAAAAIPQRR
     EEALPAEITY PADLPVVSRR EDIAKAISEN QVVVIAGETG SGKTTQIPKI CLDLGRGRRG
     LIGHTQPRRL AARTVAERIA DELGQKVGES VGYAIRFDDQ VGHSTSVKLM TDGILLAEMQ
     RDRYLNAYDT IIIDEAHERS LNIDFLLGYL KQLLPKRPDL KVIITSATID PERFAQHFAS
     GGGDGARGAG ASAAGGAGAG GAGGAGSAEV KPAPIVEVSG RTYPVEILYR PLVRELPDGK
     EVDIDPIDGL CDAIEELMGY GNGDILCFFA SEREIRDAME VIEGKKWKGV EVTPLFGRLS
     NQEQHRVFQP HSGRRIVLAT NIAETSLTVP GIHYVVDTGT ARISRYSTRT KVQRLPIEPI
     SQASAQQRSG RCGRVADGVA IRLYSEEDFL SRPEFTDPEI LRTNLASVIL HMASLRLGDI
     AEFPFVQAPA PKAIRDGLLL LHELGALGES ERDGLPVLTQ VGKDLAKIPV DPRLARMMVE
     AQTQGCLHDV IVLVAGMTVQ DVRERPLEYQ AQADQQHARF KDPESDFMAM LKLWDYLQES
     RSELSGNAFR KKMKKEFLHY LRIREWRDLV RQLSEVTAQL GWAKLHEVAG ERDRDAIHRS
     LLAGLLSQIG SRETESKEFH GARGAKFMIF PGSALAKKPP RFIMAAELVE TSRLWARDAA
     KIEPEWVERL AEGLLKHSYS EPHWSTKRAA AMAYQRSTLY GVTIVADRLV PYHRVDRAAA
     RDMFIREALI AGEWTTHHHF FHENLAKLDA ATGVEEKVRR RGLVADEDRL FEFYDARLPA
     NITTGRHFDS WWKKKRRTDP ELLDFDPDKL LSDDAHAISE EAFPDRWSKG DIDYDLMYRF
     EPGHKEDGVT IRIPVPLLAN MDTEGFDWLV PGLRGELLTE LIRSLPKGIR RTVVPAPDFA
     ERALPLLKPY ISPLNEQLAE ALRSLGAKGI DALDFQPAKL PNHLKMNYAA VDKRGKIIDC
     DRDLDALKHR QAPKISSSVS RVGRAVEMAA AKAWTPETLG AIDDKATTVV DGHEVAVYPA
     LVATAEGVEV RAMPTKAQAD ASMLTATLTL LMREIKVNTN QMIKGLGLKE RVAVQNYPHG
     GAEGLVDDAR VTAIRDLLLA AGGPVRDPEG FGELKAKIAP QVPGEVRKHV VTLAPALADY
     LSVAQELDKW EGDSIEDMKQ QLAFLLPEHA ISRHGMQRLR HLPRYLRAMK QRLGDLELDS
     ERDALRQDEI DEVKAYLRAK LRNLPGGRTS AAALKDVQWL IQELRVSLFA QQLGTARPAS
     VRRVKKAIDA LPAAN
//