ID   A0A1I2S3X1_9BACT        Unreviewed;       839 AA.
AC   A0A1I2S3X1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=Zinc-dependent metalloprotease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SAMN04487988_10473 {ECO:0000313|EMBL:SFG46449.1};
OS   Algoriphagus hitonicola.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Algoriphagus.
OX   NCBI_TaxID=435880 {ECO:0000313|EMBL:SFG46449.1, ECO:0000313|Proteomes:UP000199642};
RN   [1] {ECO:0000313|EMBL:SFG46449.1, ECO:0000313|Proteomes:UP000199642}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19315 {ECO:0000313|EMBL:SFG46449.1,
RC   ECO:0000313|Proteomes:UP000199642};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOPC01000004; SFG46449.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2S3X1; -.
DR   STRING; 435880.SAMN04487988_10473; -.
DR   OrthoDB; 9776599at2; -.
DR   Proteomes; UP000199642; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   CDD; cd04276; ZnMc_MMP_like_2; 1.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   InterPro; IPR033413; DUF5117.
DR   InterPro; IPR033428; DUF5118.
DR   InterPro; IPR032534; EcxA_zinc-bd.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR034032; Zn_MMP-like_bac.
DR   PANTHER; PTHR38478; PEPTIDASE M1A AND M12B; 1.
DR   PANTHER; PTHR38478:SF1; ZINC DEPENDENT METALLOPROTEASE DOMAIN LIPOPROTEIN; 1.
DR   Pfam; PF16313; DUF4953; 1.
DR   Pfam; PF17148; DUF5117; 1.
DR   Pfam; PF17162; DUF5118; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
FT   DOMAIN          56..105
FT                   /note="DUF5118"
FT                   /evidence="ECO:0000259|Pfam:PF17162"
FT   DOMAIN          113..300
FT                   /note="DUF5117"
FT                   /evidence="ECO:0000259|Pfam:PF17148"
FT   DOMAIN          436..744
FT                   /note="EcxA zinc-binding"
FT                   /evidence="ECO:0000259|Pfam:PF16313"
FT   REGION          35..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   839 AA;  95497 MW;  144CAA426D356E68 CRC64;
     MKNTLPKFLR RFTLLVGIFG VMFYSEDSFA QRKKKKDAKN AATTTAPAKP ANGKGPKPYK
     EVITKEAESK DGLFKVHQID EKYFYEIPDS LFGRDMLMVT TIAKTADGIG YGGERTNTLM
     LRWEKDEDNV LLRVVSVDNY APDSLPIAMA VKNSNLEPIL QRFEVKSKAT DSTGTVIEAT
     DLFAKDVPAL GLQRNRRTQY RVQRLDAERS YIEHIHTYPI NIEARYVMTY AAQNPPSNST
     TGLITLEMNS SMVLLPAEPM MQRLSDRRVG WFSRSYVDYG ADAQKAESRR YLDRWRLEVK
     PEDMEKFKRG ELVEPKKQIV YYIDPATPKK WVPYLKQGVE DWQKAFEAAG FKNAIIAKEA
     PTPEEDPTWS PEDARYSVIR YFASDIQNAY GPHVSDPRSG EIIESDIGWY HNVMNLLRNW
     YFIQTAAVNP DARSVQFKDE VMGRLIRFVS AHEVGHTLGL PHNFASSNAY PVEKLRDAEF
     TKEMGTAPSI MDYARFNYVA QPEDEGVSLM PDVGPYDKYA ISWGYRPIPE ASTPEEEQAI
     LDQWIMEKQG DPVFRYGRQG NSYDPTTQSE DLGDNSMEAS EYGIANLKRI MPNLMEWTAE
     EDKPFKDFSD LEEMYGQVLG QFNRYMGHVR THVGGVMEVY RASGQDEPVY THNSKEMQKS
     AVSFLNENLF ATPDWLMDDQ IIARTGDFGA LERIRGLQVG ALNGILEWGR LGRVIENEAI
     NGDEAYNISE LFDDLRSGIW GELAGGRAID VHRRSLQRAH IERLELMLTG DEPNLPAAFR
     RFAGPQINAS QSDIRPIARG ELKTLQRQIN AAIGRTSDRM SKLHLEDLSE RIDMILDPQ
//