ID   A0A1I2TG31_9FIRM        Unreviewed;       854 AA.
AC   A0A1I2TG31;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:SFG63835.1};
GN   ORFNames=SAMN04487761_1333 {ECO:0000313|EMBL:SFG63835.1};
OS   Lachnospiraceae bacterium C7.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1792306 {ECO:0000313|EMBL:SFG63835.1, ECO:0000313|Proteomes:UP000198643};
RN   [1] {ECO:0000313|EMBL:SFG63835.1, ECO:0000313|Proteomes:UP000198643}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C7 {ECO:0000313|EMBL:SFG63835.1,
RC   ECO:0000313|Proteomes:UP000198643};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
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DR   EMBL; FOPE01000033; SFG63835.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2TG31; -.
DR   STRING; 1792306.SAMN04487761_1333; -.
DR   OrthoDB; 9762066at2; -.
DR   Proteomes; UP000198643; Unassembled WGS sequence.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006101; Glyco_hydro_2.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR023230; Glyco_hydro_2_CS.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   PRINTS; PR00132; GLHYDRLASE2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198643}.
FT   DOMAIN          55..155
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          223..311
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          316..591
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
SQ   SEQUENCE   854 AA;  97865 MW;  F2AD6E87764BFB12 CRC64;
     MEKIYINDGW KFTTNFSDKL LLNELDPDIA GALEDVRIPH TVKEVAYDYF DEGEYQMVSG
     YRRALFAPSD WKNKKVMLTF EGVAHKATVY LNGEQVTTHM CGYTAFTVDL SNKIKYDTDN
     ILTVKVDSRE NLNAPPFGYV IDYMTFGGIY RDVYVEISNE NFISDVFPLI LLKNSEILNA
     DLISNENVSE EVSGYKVKKT NIETKVSLHV KLSDKLQKDK AVLDAETFVE IKHKLLDKNG
     LLYSEWSTKD KDLLVESKIK EHTEKINISI KREIENVFLW DTKYPNLYTL ITELYIDGDK
     VDTRKDKIGF RKVGFKSDGF YLNNKKFKLR GLNRHQSYPY VGYAMPKSMQ QYDADILKNE
     LGLNAVRTSH YPQSQHFINR CDEIGLLVFT EIPGWQHIGD EEWKNQAVLN TKEMIKQYRN
     HPSVFLWGVR INESKDDDEF YKKTNEVARK LDPTRATGGV RAHKGSSLLE DVYTYNDFVH
     SGDNKGCEPK KNVTSHMEKA YLISEYNGHM YPTKAFDAEE HQAGHLMRHV NVLDAVAKEK
     DIAGSFGWCM FDYNTHKDFG SGDRICYHGV MDMFRNPKMA ALIYACQQEK VPVLDISSSM
     DIGEHPGCNR GKIYIFSNAD SVKMYKNGKF IKEYKQKDSP YKHIKHGPIL IDDFIGDLIY
     KNEKGFTKKQ ADDIKYALNY TALNGYGRYP WKVIKIALKA LTIYGMKTSD AVPLFNKYIG
     DWGGTSTVYK FEAIKNGKVV KTITKEPMKE KHLHTKVSNT KLVEGNSYDV AEVRMEMHDE
     NGNRLSFYNE PVVLKAEGEI EIIGPEITSF RGGMTGTYIK TIGKAGTGKL TISDPNKKWE
     SKEITFEISK ISNN
//