ID   A0A1I2TUA1_9BACT        Unreviewed;       436 AA.
AC   A0A1I2TUA1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=HlyD family secretion protein {ECO:0000313|EMBL:SFG68460.1};
GN   ORFNames=SAMN04487988_106215 {ECO:0000313|EMBL:SFG68460.1};
OS   Algoriphagus hitonicola.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Algoriphagus.
OX   NCBI_TaxID=435880 {ECO:0000313|EMBL:SFG68460.1, ECO:0000313|Proteomes:UP000199642};
RN   [1] {ECO:0000313|EMBL:SFG68460.1, ECO:0000313|Proteomes:UP000199642}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19315 {ECO:0000313|EMBL:SFG68460.1,
RC   ECO:0000313|Proteomes:UP000199642};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
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DR   EMBL; FOPC01000006; SFG68460.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2TUA1; -.
DR   STRING; 435880.SAMN04487988_106215; -.
DR   OrthoDB; 9809068at2; -.
DR   Proteomes; UP000199642; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.420.20; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   NCBIfam; TIGR01730; RND_mfp; 1.
DR   PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR   PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          55..292
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
FT   COILED          106..178
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   436 AA;  47504 MW;  6D142DE9BD1484B1 CRC64;
     MATKKSNKLL YYLLGIVGAL IVFAIIGRSL GWIGGENVTQ VEIAKVGKNS IIEKVSASGE
     IQPEIEVNLS PDVAGEIIEL NIQEGDSVEM GKLLVKIRPD NFISALDRSR ANLNQQQANL
     AQSKASLQRA EAQFTRSELE YKRQKTLYEQ KAISDADFEQ AEANYITAQK DLEAAKQSVI
     AAEFVVKSSQ ATVNEAAENL RLTNVYSPVS GIVSNLLVEK GERVVGTQQM AGTEMLTIAD
     LTRMEVRVDV NENDIVRLAM GDTTLIEVDA YSTSGKTFKG IVTSIANTAN TKASSDAVTE
     FKVKIRILNS SYQDLVDAGN KYPFRPGMTA SVEIITNQKD NVLSVPLAAV TTRENKVDTL
     ADGTTRPQEL VFLVENGEAK MTKIKTGISD FQFIEVLEGL SENQEVVSGP YYTVSKELEE
     GDKVEKASTP LSSSNQ
//