ID   A0A1I2UFH8_9SPHI        Unreviewed;       281 AA.
AC   A0A1I2UFH8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:SFG75099.1};
GN   ORFNames=SAMN04489864_10298 {ECO:0000313|EMBL:SFG75099.1};
OS   Pedobacter insulae.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=414048 {ECO:0000313|EMBL:SFG75099.1, ECO:0000313|Proteomes:UP000199666};
RN   [1] {ECO:0000313|EMBL:SFG75099.1, ECO:0000313|Proteomes:UP000199666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18684 {ECO:0000313|EMBL:SFG75099.1,
RC   ECO:0000313|Proteomes:UP000199666};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC       {ECO:0000256|ARBA:ARBA00009405}.
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DR   EMBL; FOPP01000002; SFG75099.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2UFH8; -.
DR   STRING; 414048.SAMN04489864_10298; -.
DR   OrthoDB; 9784013at2; -.
DR   Proteomes; UP000199666; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR   CDD; cd07938; DRE_TIM_HMGL; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR043594; HMGL.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:SFG75099.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199666}.
FT   DOMAIN          1..270
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
SQ   SEQUENCE   281 AA;  31007 MW;  2EE90D92A8867FB5 CRC64;
     MKLIECPRDA MQGLHDFVPT VDKTSYINLL LQVGFDTIDF GSFVSPKAIP QLRDTSEVLA
     NLDLSSTRTK LLAIVANLRG VQEAITHQSI NYLGFPFSIS ETFQQRNTNS SISQSLNTVE
     EMLNLCDKHQ KTAVVYLSMG FGNPYGDEWN IEIVAHWADE LIKRGVGILS ISDTTGVSTP
     EKINAILPGL IKTFNKTEIG IHLHSTPETR IEKIAAAYAA GCTRFDSAVK GFGGCPMATD
     DLTGNLATED LIYFLESRGE KLGLNKDYWQ EAMLFSSKIF S
//