ID   A0A1I2V6T9_9FIRM        Unreviewed;       172 AA.
AC   A0A1I2V6T9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Transcription repressor NadR {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SAMN05660649_02896 {ECO:0000313|EMBL:SFG84129.1};
OS   Desulfotruncus arcticus DSM 17038.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfallaceae;
OC   Desulfotruncus.
OX   NCBI_TaxID=1121424 {ECO:0000313|EMBL:SFG84129.1, ECO:0000313|Proteomes:UP000199337};
RN   [1] {ECO:0000313|Proteomes:UP000199337}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17038 {ECO:0000313|Proteomes:UP000199337};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOOX01000010; SFG84129.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2V6T9; -.
DR   STRING; 341036.SAMN05660649_02896; -.
DR   Proteomes; UP000199337; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   Gene3D; 3.30.1340.20; 3H domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR035922; 3H_dom_sf.
DR   InterPro; IPR004173; 3H_domain.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR026043; NadR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR40068; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   PANTHER; PTHR40068:SF1; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   Pfam; PF02829; 3H; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   PIRSF; PIRSF037847; NiaR; 1.
DR   SUPFAM; SSF75500; Putative transcriptional regulator TM1602, C-terminal domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR037847-1};
KW   Nickel {ECO:0000256|PIRSR:PIRSR037847-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199337}.
FT   DOMAIN          7..59
FT                   /note="Helix-turn-helix type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08279"
FT   DOMAIN          74..169
FT                   /note="3H"
FT                   /evidence="ECO:0000259|Pfam:PF02829"
FT   BINDING         77
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         85
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         144
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         146
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
SQ   SEQUENCE   172 AA;  19260 MW;  7E0AC6448D93DF53 CRC64;
     MGMSEKRREK IIKALTDNAG PVSGSALAKQ FKVSRQVIVQ DVAILRAKGY EIMATPQGYL
     LPQEANVCEQ AVLAVRHTPL ETGAELNTMV DFGLKVLDVQ VEHPIYGELK GYLMLESRQD
     VKRFVERLKV EGVPLLSSLT NGVHLHTVEY RRREDLEGAR QALHKHGFLI SE
//