ID   A0A1I2V833_9EURY        Unreviewed;       553 AA.
AC   A0A1I2V833;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=aldehyde ferredoxin oxidoreductase {ECO:0000256|ARBA:ARBA00012818};
DE            EC=1.2.7.5 {ECO:0000256|ARBA:ARBA00012818};
GN   ORFNames=SAMN04488063_3068 {ECO:0000313|EMBL:SFG84357.1};
OS   Halopelagius inordinatus.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae.
OX   NCBI_TaxID=553467 {ECO:0000313|EMBL:SFG84357.1, ECO:0000313|Proteomes:UP000198876};
RN   [1] {ECO:0000313|Proteomes:UP000198876}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.7739 {ECO:0000313|Proteomes:UP000198876};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a
CC         carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin];
CC         Xref=Rhea:RHEA:16421, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17478,
CC         ChEBI:CHEBI:29067, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738; EC=1.2.7.5;
CC         Evidence={ECO:0000256|ARBA:ARBA00001714};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the AOR/FOR family.
CC       {ECO:0000256|ARBA:ARBA00011032}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOOQ01000005; SFG84357.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2V833; -.
DR   STRING; 553467.SAMN04488063_3068; -.
DR   OrthoDB; 30771at2157; -.
DR   Proteomes; UP000198876; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0033726; F:aldehyde ferredoxin oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.569.10; Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2; 1.
DR   Gene3D; 1.10.599.10; Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 3; 1.
DR   Gene3D; 3.60.9.10; Aldehyde ferredoxin oxidoreductase, N-terminal domain; 1.
DR   InterPro; IPR013984; Ald_Fedxn_OxRdtase_dom2.
DR   InterPro; IPR013985; Ald_Fedxn_OxRdtase_dom3.
DR   InterPro; IPR013983; Ald_Fedxn_OxRdtase_N.
DR   InterPro; IPR036503; Ald_Fedxn_OxRdtase_N_sf.
DR   InterPro; IPR001203; OxRdtase_Ald_Fedxn_C.
DR   InterPro; IPR036021; Tungsten_al_ferr_oxy-like_C.
DR   PANTHER; PTHR30038; ALDEHYDE FERREDOXIN OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR30038:SF7; TUNGSTEN-CONTAINING GLYCERALDEHYDE-3-PHOSPHATE:FERREDOXIN OXIDOREDUCTASE; 1.
DR   Pfam; PF01314; AFOR_C; 1.
DR   Pfam; PF02730; AFOR_N; 1.
DR   SMART; SM00790; AFOR_N; 1.
DR   SUPFAM; SSF48310; Aldehyde ferredoxin oxidoreductase, C-terminal domains; 1.
DR   SUPFAM; SSF56228; Aldehyde ferredoxin oxidoreductase, N-terminal domain; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198876}.
FT   DOMAIN          5..206
FT                   /note="Aldehyde ferredoxin oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00790"
SQ   SEQUENCE   553 AA;  60044 MW;  DB0B45A4DD2A2C98 CRC64;
     MLHSKGPLVS IDVGTRETKR TDVTDVLESY IGGRGVATKL AHDRIPFDVD PLGPENRVLF
     TTGPMQASNM SFTGRMNCTA VSPLTDGLLS SNAGGFMSRH FADTGNAAVE FVGESDELVV
     VHVRDDGVRF EEVPNLSGAT VPETVEYLDS EHDIGSDQTA IVGPAGENEV RFASVMTSEE
     RAFGRGGLGA VLGSKNVKAV TFEGDSAPEI EIPAGQMEIH REAATDDNIM KEQGTVAVMD
     LANEVDGLPS YYFSEQTFAG VEGINGDAVA EKKYKKGTCS ACAFACKLPT RDEERGVETE
     GPEFEVAMAF GSNSGVDDIV DVMKSNQLCD EYGLDAISAG NTVAAYLAAE DEFGNRELIW
     DLVEKIAHRE GVGDTLAEGI DRVHDELGVE NWTVKGMDFA AHEGRVLHGQ GLSYAVANRG
     ADHMYATFYS VEYPLVPQDQ AVDPEGAVGK AGILAEREDL MALNDSGVVC KFSRDYMTPE
     RYEMLFGADF EELLDVGART VTLERHFNNK RGFDRDDDRL PYDLPEFEAA LEEYYETRGW
     TEEGVVPDGR VPV
//