ID A0A1I2VHQ2_9FIRM Unreviewed; 383 AA.
AC A0A1I2VHQ2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=SAMN05660649_02944 {ECO:0000313|EMBL:SFG86996.1};
OS Desulfotruncus arcticus DSM 17038.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfallaceae;
OC Desulfotruncus.
OX NCBI_TaxID=1121424 {ECO:0000313|EMBL:SFG86996.1, ECO:0000313|Proteomes:UP000199337};
RN [1] {ECO:0000313|Proteomes:UP000199337}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17038 {ECO:0000313|Proteomes:UP000199337};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR EMBL; FOOX01000011; SFG86996.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2VHQ2; -.
DR STRING; 341036.SAMN05660649_02944; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000199337; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000199337}.
FT DOMAIN 24..366
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 383 AA; 42699 MW; FBA369AD4D2AA0FD CRC64;
MMKVLVVFGT RPEAIKMAPL VQLLQRDEQL DCRVAVTAQH REMLDQVLRL FNIVPDHDLN
IMRSGQTLFD ITGRALAGLQ KVLELEKPDL VLVHGDTTTT FVAALAAYYM QIPVGHVEAG
LRTGNKYSPY PEEMNRRLTG ALAELNFAPT VKARANLLRE GVNPDSIFVT GNTVIDALMA
TVRPDYRFND PLLNRLLAEE GRIILMTTHR RENLGAPMRD IYLALRDTLD NYPDIRVIFP
VHKNPAVRQV VQEVLGGNDR VHLVEPLDYE PHINLMSRCY LVLTDSGGMQ EEAPALGKPV
LVLRNTTERP EAVDAGTVIL VGTDRQTVRE ETGRLLSDAG HYRSMSEAIN PYGDGRACGR
IAQAIKFSYR LAAEKPVEFS PLA
//
