ID   A0A1I2WUZ7_9SPHI        Unreviewed;       460 AA.
AC   A0A1I2WUZ7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Thiol-disulfide isomerase or thioredoxin {ECO:0000313|EMBL:SFH05123.1};
GN   ORFNames=SAMN04489864_104302 {ECO:0000313|EMBL:SFH05123.1};
OS   Pedobacter insulae.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=414048 {ECO:0000313|EMBL:SFH05123.1, ECO:0000313|Proteomes:UP000199666};
RN   [1] {ECO:0000313|EMBL:SFH05123.1, ECO:0000313|Proteomes:UP000199666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18684 {ECO:0000313|EMBL:SFH05123.1,
RC   ECO:0000313|Proteomes:UP000199666};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOPP01000004; SFH05123.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2WUZ7; -.
DR   STRING; 414048.SAMN04489864_104302; -.
DR   OrthoDB; 1118217at2; -.
DR   Proteomes; UP000199666; Unassembled WGS sequence.
DR   GO; GO:0016209; F:antioxidant activity; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd02966; TlpA_like_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR000866; AhpC/TSA.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR42852; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE; 1.
DR   PANTHER; PTHR42852:SF6; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE; 1.
DR   Pfam; PF00578; AhpC-TSA; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:SFH05123.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199666};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..460
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011796098"
FT   DOMAIN          34..189
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
SQ   SEQUENCE   460 AA;  51837 MW;  E483D5AEF59B62BD CRC64;
     MKKITIYIVM ALLCLNFKAQ AQDNKAVDVT LKGIQIGQKV PDITITGLHN YRDTNGKLAT
     TAKLSDFKGK LLILDFWATW CSPCVAMIPK MDSLQKSFGD KIQFLSATYQ TEKEVLPFLE
     KFEKQQGKHY NLPVVTSSKQ LHQLFPHTTL PHYIWVDGSG LVKAVTGYEE VNTENISKVF
     ANAVELERKK DMNVVYNKEI PLLINGNGGN GSNLIYHSIL TGYIDGLGSM QRIRSAEKST
     KIIRAINYPL LNLMQLAYGN GQYNWKKNRT DVEVSSPEKI SSGLKGRAVE EWLKAGNGYS
     YELILPNNSK KNLWEEMKSD LAELFDVYEI NIEKRKKTCL AIVKTTDENL FNKHHTDYLY
     KATADELLIE NTFFSVLTWN LENVYLKGYP NPIINDTGYD GKIGINLQGD LKSLAGLDIS
     LAKYGLKLVE KELFIPVLVI KDKHVNTGVA ETAGKKTFTN
//