ID   A0A1I2Y041_9GAMM        Unreviewed;      1032 AA.
AC   A0A1I2Y041;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Multidrug efflux pump subunit AcrB {ECO:0000313|EMBL:SFH19118.1};
GN   ORFNames=SAMN04487959_101161 {ECO:0000313|EMBL:SFH19118.1};
OS   Halomonas xianhensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=442341 {ECO:0000313|EMBL:SFH19118.1, ECO:0000313|Proteomes:UP000199040};
RN   [1] {ECO:0000313|EMBL:SFH19118.1, ECO:0000313|Proteomes:UP000199040}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.6848 {ECO:0000313|EMBL:SFH19118.1,
RC   ECO:0000313|Proteomes:UP000199040};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOPY01000001; SFH19118.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2Y041; -.
DR   STRING; 442341.SAMN04487959_101161; -.
DR   Proteomes; UP000199040; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF33; RND SUPERFAMILY EFFLUX PUMP PERMEASE COMPONENT; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199040};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        332..352
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        359..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        384..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        429..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        456..480
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        531..550
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        861..878
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        885..905
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        911..936
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        957..976
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        988..1014
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1032 AA;  111455 MW;  D3AF59BD549E1AAB CRC64;
     MMRQGPIAWM TRHGVAPNLL MLALLIGGLL ASLHIKKEVF PDFTLESIAI SVSYSGATPE
     EVEQSLLLAI EAELADIEGI DEITSTASEG SGSVEVDLLD GVDTMRVYQE IQQAVDSITT
     FPDAADPPRF SLAGRSRGVL ELQLHGDVDA LTLSELGEQV RTELMSGTDI TKVELSGNRE
     REIQVLLDEE AIRRYGLSHF ALASLIADEA LDLAGGSLDT RDSEWLIRYQ GRRESAQAFA
     DLPVRTTTNG GVIRLGDIAE VREGLAESDR EVLFNGEPGL TLDVYQVGNQ TPLGISETVR
     GELDRLRADL PQDVSLTLGW DSSEIYRERL DLLLKNAWMG LALVLVLMAL FLEARLAFWV
     TLGIPTAFLG ALLFLPWMGV SINMMSMFAF IIALGIVVDD AIMVGENIYA YREQGHSVRE
     AAVRGAREIA VPISFAVLSN IVAFLPLLYL PGFLGMIMGV VPLVVVTVFL VSWLEALFIL
     PAHLAHSRKH DTLPAWQQPL ERLRLFMQGG LHRFTHHFFA PFLQRTLDQR ALTVAIGVAI
     LCVALAYAMS GRLGFSLMPR AESDRVQASV TLPAGSPIAA DQAVRDALLA SALRLAERDG
     GPIIESTRTH LSGDSLEVRL DLATESLHDW PPSRVAREWR QLAGELSGVQ SVRFEADVGG
     PGSGAALTVR LSHSQSAMLE QAATALADAL NGFDGVTEIN SGIANGKPQL SIQLSPEGRA
     LGLTGADLAA QLRGPLQGAT ALEQQRGSTT VSVEVRLPPE DRDSLSELGR LPIVTPDGVE
     VPLSRVAKIS TGRASAELTR VDGRRVISVT ADVTDGPQIN RILNTLQAEV YPDLRQRYPG
     LAIGAGGRQE ETADNLAALK TAMWLTLAAL YALLAIPFRS YLQPLLVMSA IPFGIIGAVV
     GHMLMGFGLS VISLLGMLAL SGVVINDALV LIDYANRRRR EGMGPREAIV AAATRRLRPI
     MMTTLTTFLG LAPMIFETSR QARFIIPMAI SLGFGILFAT VILLILVPCL YLMLENLRAR
     LGLSSATVTE AS
//