ID   A0A1I2Z845_9PROT        Unreviewed;       885 AA.
AC   A0A1I2Z845;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Dolichol-phosphate mannosyltransferase {ECO:0000313|EMBL:SFH33241.1};
GN   ORFNames=SAMN05216299_10731 {ECO:0000313|EMBL:SFH33241.1};
OS   Nitrosospira sp. Nsp14.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=1855333 {ECO:0000313|EMBL:SFH33241.1, ECO:0000313|Proteomes:UP000198772};
RN   [1] {ECO:0000313|EMBL:SFH33241.1, ECO:0000313|Proteomes:UP000198772}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nsp14 {ECO:0000313|EMBL:SFH33241.1,
RC   ECO:0000313|Proteomes:UP000198772};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FOPV01000007; SFH33241.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2Z845; -.
DR   STRING; 1855333.SAMN05216299_10731; -.
DR   Proteomes; UP000198772; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProt.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR007267; GtrA_DPMS_TM.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR038731; RgtA/B/C-like.
DR   PANTHER; PTHR33908; MANNOSYLTRANSFERASE YKCB-RELATED; 1.
DR   PANTHER; PTHR33908:SF12; PMT_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   Pfam; PF04138; GtrA; 1.
DR   Pfam; PF13231; PMT_2; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW   ECO:0000313|EMBL:SFH33241.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198772};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SFH33241.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        261..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        326..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        455..476
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        488..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        532..564
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        576..596
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        622..643
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        659..679
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        685..704
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        716..736
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          39..167
FT                   /note="Glycosyltransferase 2-like"
FT                   /evidence="ECO:0000259|Pfam:PF00535"
FT   DOMAIN          262..377
FT                   /note="GtrA/DPMS transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04138"
FT   DOMAIN          434..594
FT                   /note="Glycosyltransferase RgtA/B/C/D-like"
FT                   /evidence="ECO:0000259|Pfam:PF13231"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   885 AA;  96481 MW;  665760831279BB82 CRC64;
     MSSLSKPTDR TGLLSLRFAP DPPAAGPSGA GGPNAIRFSV VVAALNDAAG IDLLMESLSA
     SNIPAESFEV IVVNDSSSEQ VAGRVRAWEN RANIRLVEPE EKLDCARSVL AGTALACGEV
     VVVMGGDFSH PLDRLPALIE SVLNGSHDVA IASRYAHPPG TGSLGNLLAW PLRHGYDAAS
     EFFVFRRDLA RLITACPDGG RILPELLMAG GGKLRVVEVP TRLGDENDAP LRAGIKQQAG
     DLQRLMTLTG STVAPGAGSR LAAVALLGAI IDAVLFLSLT GQGAGLAMAH ILSFLPAVAV
     SYFLYSKSSR RTQQNDGRMR SPQIGRFVLV SMLALSMRGG VLALLVNAWH IPAFIAIFPA
     IVAAAVILYL GSGFYVFSAG SAFSFPDVRW WVASFGIVAF AVLLRLIYIG AAQLIPDEAY
     YWNYAQHMDL SFFDHPPMVA WLIWLGTGLF GDNEFGVRVG AVICGLIAMG YLYALAHNLY
     DKSTAMRAVL LLAVLPFGCV TGALMTPDAP LMATWAATLY YMERALIADR RWAWLGMGIA
     FGLGILSKYT LGLMGVAALV FVVLDPESRR WLRRPHAYLA AALALLLFSP VIIWNMENGW
     ASILFQSERA TGIGNQFSLH LLFFHMLLML TPVGLLAAAL ALWPGRDQRP SPYANRRQLF
     VRVFTVVPLA VFFGLSLVGA PKFHWTAPVW LAVLPTIAWM MGSAGNWRNI TRRVAAAWKP
     TIVVCLFVYA IALHYVTLGI PGVPYKGFAE HYFWHETVPE IEKLAAEIQH QTGQKPIVVG
     MSKWSVSAAL SFYGNKAEPM EIRARNMFHQ SAAAYDFWYP SQSPTTRPIL LVGMKPHQLE
     HDIHGVDNIT PSLVRPGPTQ ELVIYRDKRP LRRVYYRVAY GYNPV
//