ID   A0A1I2ZJB8_9SPHI        Unreviewed;       488 AA.
AC   A0A1I2ZJB8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Thiol-disulfide isomerase or thioredoxin {ECO:0000313|EMBL:SFH37676.1};
GN   ORFNames=SAMN04489864_11057 {ECO:0000313|EMBL:SFH37676.1};
OS   Pedobacter insulae.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=414048 {ECO:0000313|EMBL:SFH37676.1, ECO:0000313|Proteomes:UP000199666};
RN   [1] {ECO:0000313|EMBL:SFH37676.1, ECO:0000313|Proteomes:UP000199666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18684 {ECO:0000313|EMBL:SFH37676.1,
RC   ECO:0000313|Proteomes:UP000199666};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOPP01000010; SFH37676.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2ZJB8; -.
DR   STRING; 414048.SAMN04489864_11057; -.
DR   OrthoDB; 983020at2; -.
DR   Proteomes; UP000199666; Unassembled WGS sequence.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   CDD; cd02966; TlpA_like_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR42852; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE; 1.
DR   PANTHER; PTHR42852:SF6; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE; 1.
DR   Pfam; PF13905; Thioredoxin_8; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Isomerase {ECO:0000313|EMBL:SFH37676.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199666};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..488
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011538196"
FT   DOMAIN          340..487
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   COILED          132..174
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   488 AA;  56293 MW;  9ABE40BD98D40D25 CRC64;
     MSKIQHTILV LISIVSSFQC LAFYEGGAKF TAQLNYTKPP DSLIVKTFTK NWTYSDYPVS
     YFKAYQKGKF RFELEEFKKP VMIMITIKQG NKRLSYSYFM EHTDNVNFEV FRNNQRDSIA
     FSGNGSEKYN LVNQLEDEFK EYFSERSKLK LTITENLESA LEKYAQMVQD YNGRKQEHIE
     KSNLSPEMKE LINLQFANYY GDWSWLLSNL FVFKKTSQEV RDQIRASYLK FSPIFTQLPT
     AGSINCHRYI GALFDRVRAD RLMGNNVGSI PLEQYYHAIT NQYSGPVRER LLAEFFMSNY
     TLQNITSSAS LSFDSLVADA RRYLGKSELL SEALDYRSRL KRGNKLTEPT FTDLLGNPFN
     LETLTGKVLL IKVWATGCGG CMDFERRLIQ DISPSFEGEQ QFKVVSINVD KRTENWINSL
     NTGKYSTRRH LNLNTGGQGL SHPFLKQLNV NALPFVLIVD KKGNIYQKLD LSIENNDIIK
     VISSAIKE
//