ID   A0A1I3BW60_9FIRM        Unreviewed;       458 AA.
AC   A0A1I3BW60;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN   ORFNames=SAMN04487830_104114 {ECO:0000313|EMBL:SFH66588.1};
OS   Pseudobutyrivibrio sp. OR37.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Pseudobutyrivibrio.
OX   NCBI_TaxID=1798186 {ECO:0000313|EMBL:SFH66588.1, ECO:0000313|Proteomes:UP000198895};
RN   [1] {ECO:0000313|Proteomes:UP000198895}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OR37 {ECO:0000313|Proteomes:UP000198895};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC       sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
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DR   EMBL; FOQF01000004; SFH66588.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3BW60; -.
DR   STRING; 1798186.SAMN04487830_104114; -.
DR   OrthoDB; 9808591at2; -.
DR   Proteomes; UP000198895; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd01335; Radical_SAM; 1.
DR   CDD; cd21124; SPASM_CteB-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR024025; SCIFF_rSAM_maturase.
DR   InterPro; IPR047602; SPASM_CteB-like.
DR   InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR   NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR   NCBIfam; TIGR03974; rSAM_six_Cys; 1.
DR   PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR   PANTHER; PTHR43273:SF8; RADICAL SAM PROTEIN-RELATED; 1.
DR   Pfam; PF13353; Fer4_12; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDG01072; dehydrogenase_like; 1.
DR   SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT   DOMAIN          92..318
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|PROSITE:PS51918"
SQ   SEQUENCE   458 AA;  52253 MW;  271090B069F4A8A5 CRC64;
     MIHQFKNNGY NIVIDINSGA IHVVDEITYE LLALWQEHGE EDAVATLKKN HSEIPAEEIE
     GIRSEINQLI EDGSLFTEDN YEPRIADFSA RPTVVKALCL HITHDCNLAC KYCFAEEGEY
     HTGKRELMSY EVGKQALDFL VANSGSRRNL EVDFFGGEPL MNWQVVKDLV AYGRSLEKEH
     NKNFRFTLTT NGVLLNEEVQ EFVNKEMGNV VLSCDGRPEI HNLMRPFRKG APSYELVMPK
     FKELAESRNQ DKYYIRGTFT RNNLDFSKDV LHLANEGFKQ ISVEPVVAQE TDDYALREED
     LPKLFEEYDN LAAEMMRRQG TEEDFNFFHF MIDLEGGPCV YKRLSGCGSG TEYLAVTPTG
     ELYPCHQFVG NTDFCLGDVW HGVQKTDVVN QFKHCNVYAK EECRNCFARF YCSGGCAANA
     YNFTGSILGN YHVGCELQKK RIECAIALKV HKSEQECE
//