ID A0A1I3IS28_9RHOB Unreviewed; 482 AA.
AC A0A1I3IS28;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Nucleobase:cation symporter-2, NCS2 family {ECO:0000313|EMBL:SFI50692.1};
GN ORFNames=SAMN04488095_1076 {ECO:0000313|EMBL:SFI50692.1};
OS Jannaschia pohangensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia.
OX NCBI_TaxID=390807 {ECO:0000313|EMBL:SFI50692.1, ECO:0000313|Proteomes:UP000199110};
RN [1] {ECO:0000313|EMBL:SFI50692.1, ECO:0000313|Proteomes:UP000199110}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19073 {ECO:0000313|EMBL:SFI50692.1,
RC ECO:0000313|Proteomes:UP000199110};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; FORA01000001; SFI50692.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3IS28; -.
DR STRING; 390807.SAMN04488095_1076; -.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000199110; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199110};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 32..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 482 AA; 49591 MW; 5F1BA25360BCB775 CRC64;
MADTSIGTAA QLRDPDYTPP LAKAVPLGIQ HVLAMFVSNV TPAIIIAGAA GFGFGSDAGA
QGFPDMTYLI QMSMLFAGTA TLFQTIGFGP VGARLPIVQG TSFAFIPIMI PLVAGKGIEA
LPALFGGVVI GGLFHTLIAT FIGKIRFALP PLVTGLVVTM IGLALVKVGI EYAAGGVPAK
AADLPEYGSL LNWSAALVVI FVTLALKFYA KGMLAVSAVV IGIFVGYFYA MAMGMVTLES
ITTSWSRAAA VSFPIPFKYG FEMSFAAIVG FCLMAFVSAV ETVGDVSGIT KGGAGREATE
KEITGATYAD GLGTAVAGVF GGFPNTSFSQ NVGLIAMTGV MSRHVVTIGA IFLIICGLVP
KVGAVIRTIP IEVLGGGVIV MFGMVVAAGI SMLSDVNWNR RNMVIFAIAL SVGLGLQLDP
QAVQYLPETV RILMTSGLLP AAVIAIVLNL ILPEELAGEA TEEVSGGMAG NGTFGARDAS
QR
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