ID A0A1I3J5J9_9SPHI Unreviewed; 327 AA.
AC A0A1I3J5J9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Lactate dehydrogenase {ECO:0000313|EMBL:SFI55248.1};
GN ORFNames=SAMN05444682_104319 {ECO:0000313|EMBL:SFI55248.1};
OS Parapedobacter indicus.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Parapedobacter.
OX NCBI_TaxID=1477437 {ECO:0000313|EMBL:SFI55248.1, ECO:0000313|Proteomes:UP000198670};
RN [1] {ECO:0000313|EMBL:SFI55248.1, ECO:0000313|Proteomes:UP000198670}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RK1 {ECO:0000313|EMBL:SFI55248.1,
RC ECO:0000313|Proteomes:UP000198670};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FOQO01000004; SFI55248.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3J5J9; -.
DR STRING; 1477437.SAMN05444682_104319; -.
DR OrthoDB; 1522997at2; -.
DR Proteomes; UP000198670; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR10996:SF257; GLYCERATE DEHYDROGENASE HPR, PEROXISOMAL; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000198670}.
FT DOMAIN 4..319
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 110..287
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 327 AA; 36276 MW; E38119F9D6DBE26C CRC64;
MKIFVTRALP EIIKQSLANE GHIVSEWTEK RDLSPAELTD YSLANDALFS IGKNQIDKHF
LTACSHLRVI ALCSVGYDHV DVDEATKFGI PIGNTPGVLS KATADTAFLL IQNVARKAIY
NHKEILRGNW GFFDPMANLG IELHGKTLGI YGLGRIGFEL ARSCRYAFDM PVIYYNRSHN
ERAEHELNAR RVSFDELLQQ SDVLSVHANL SEETEGIFDR HAFSKMKASS IFINTARGAI
HNETDLQLAL EEGQIWGAGL DVTHPEPMAP GNPLLAMPTV AILPHIGSAT IETRMKMMQL
TVENILAGLN GQRLPYCVNP KVYGVEH
//
