ID A0A1I3LQM1_9BACL Unreviewed; 341 AA.
AC A0A1I3LQM1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Nickel import system ATP-binding protein NikE {ECO:0000256|ARBA:ARBA00040286};
DE EC=7.2.2.11 {ECO:0000256|ARBA:ARBA00039098};
GN ORFNames=SAMN05421852_102287 {ECO:0000313|EMBL:SFI86983.1};
OS Thermoflavimicrobium dichotomicum.
OC Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC Thermoflavimicrobium.
OX NCBI_TaxID=46223 {ECO:0000313|EMBL:SFI86983.1, ECO:0000313|Proteomes:UP000199545};
RN [1] {ECO:0000313|EMBL:SFI86983.1, ECO:0000313|Proteomes:UP000199545}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44778 {ECO:0000313|EMBL:SFI86983.1,
RC ECO:0000313|Proteomes:UP000199545};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + Ni(2+)(out) = ADP + H(+) + Ni(2+)(in) + phosphate;
CC Xref=Rhea:RHEA:15557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:49786,
CC ChEBI:CHEBI:456216; EC=7.2.2.11;
CC Evidence={ECO:0000256|ARBA:ARBA00037009};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:15558;
CC Evidence={ECO:0000256|ARBA:ARBA00037009};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (NikD and
CC NikE), two transmembrane proteins (NikB and NikC) and a solute-binding
CC protein (NikA). {ECO:0000256|ARBA:ARBA00038669}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC {ECO:0000256|ARBA:ARBA00005417}.
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DR EMBL; FORR01000002; SFI86983.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3LQM1; -.
DR STRING; 46223.SAMN05421852_102287; -.
DR Proteomes; UP000199545; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0015675; P:nickel cation transport; IEA:UniProtKB-KW.
DR GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR CDD; cd03257; ABC_NikE_OppD_transporters; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013563; Oligopep_ABC_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01727; oligo_HPY; 1.
DR PANTHER; PTHR43776:SF7; D,D-DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DDPF-RELATED; 1.
DR PANTHER; PTHR43776; TRANSPORT ATP-BINDING PROTEIN; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF08352; oligo_HPY; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SFI86983.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199545};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 30..273
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 341 AA; 38605 MW; CDE5A277B4238F4F CRC64;
MNQENKIQAV KQEELEAKKK EDKAEQDIIL DVQNLKKHFK IGRQIVQAVD GVTFQVRRGE
TLGLVGESGC GKSTVGRTLI RLYSATDGKV IFNGEDVHQL KGQKLKEFNR KMQMIFQDPY
ASLNPRMKVL DIIAEGMDIH GLATGEEREK RVVELLETVG LNKSHLERYP HEFSGGQRQR
IGIARALAVE PDFIIADEPI SALDVSIQAQ VVNLMKRLQK ERGLTYLFIA HDLSMVKYIS
DRVGVMYLGN LVELADSDKL YEEPLHPYTE ALLSAVPIPD PKVAKTRERI ILQGDVPSPI
NPPSGCRFRT RCPKVKDICS QVIPEWKEIK ENHWVACHLY S
//
