ID A0A1I3M424_9PSEU Unreviewed; 346 AA.
AC A0A1I3M424;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:SFI91550.1};
GN ORFNames=SAMN05421835_102164 {ECO:0000313|EMBL:SFI91550.1};
OS Amycolatopsis sacchari.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=115433 {ECO:0000313|EMBL:SFI91550.1, ECO:0000313|Proteomes:UP000199025};
RN [1] {ECO:0000313|EMBL:SFI91550.1, ECO:0000313|Proteomes:UP000199025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44468 {ECO:0000313|EMBL:SFI91550.1,
RC ECO:0000313|Proteomes:UP000199025};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FORP01000002; SFI91550.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3M424; -.
DR STRING; 115433.SAMN05421835_102164; -.
DR OrthoDB; 3226810at2; -.
DR Proteomes; UP000199025; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000199025};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 7..61
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 346 AA; 36935 MW; CAD8B3887A7F8C33 CRC64;
MIARSHVTLE DVAEVANVSL ATASRVLNGT TNVREDLRDR VLAAATDLAY TPNVHAQALA
GASHPTVGVV CHDVSDPYFA AVARGVLRAA DRNGLLVMLA STFRDPEKEI AYVSTLRRQR
ASAIVLAGSG FEDRAWERAL AAELEPYRRG GGQVAVIGRH RNLKVDSVQP ENRSGAKALA
GALLGLGHRR FAVLSGPRTM TTVVDRFTGF REGLAEAGIE LSERDVFEAS FDRDGGQAAA
EEFLSGRHRA TCVFAVSDQM AIGALAAFRA AGRDVPGDVS LAGFGNIPVA RDLNPALTTV
ALPLEDLGEQ AMELALSGTP TGRSRTRRMA GEVLLRDSTA RTRRRR
//
