ID A0A1I3M925_9BACL Unreviewed; 757 AA.
AC A0A1I3M925;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=SAMN02799624_02755 {ECO:0000313|EMBL:SFI93473.1};
OS Paenibacillus sp. UNC496MF.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1502753 {ECO:0000313|EMBL:SFI93473.1, ECO:0000313|Proteomes:UP000198714};
RN [1] {ECO:0000313|EMBL:SFI93473.1, ECO:0000313|Proteomes:UP000198714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UNC496MF {ECO:0000313|EMBL:SFI93473.1,
RC ECO:0000313|Proteomes:UP000198714};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; FORE01000007; SFI93473.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3M925; -.
DR STRING; 1502753.SAMN02799624_02755; -.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000198714; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR029491; Helicase_HTH.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF14493; HTH_40; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:SFI93473.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198714}.
FT DOMAIN 26..195
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 219..363
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 521..601
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 757 AA; 82775 MW; F8BDEF2EF2F16C14 CRC64;
MHQEALQTLK QVYGYDSFRK GQSDIIEGLL DGKDTLAILP TGGGKSVCYQ IPAMLLPGTT
IVVSPLISLM KDQVDALNRL GVSAAYLNSS LDAATYREVV RQTSQGAYKM LYVAPERLDG
GMFESLSSQL HIPLIAIDEA HCVSQWGHDF RPSYRQLAGW IGRLENRPPV AAFTATATPE
VSEDIAAMLG LHRPNIFVTG FARTNLTLSV VTGTDKRKFL RDFVRQRPDQ SGIVYTATRK
EAEEVCDDLS KLGVSVGKYH GGLNDEERAD AQERFRFDDN RVMVATNAFG MGIDKPNVRY
VVHWQMPGDV ESYYQEAGRA GRDGEESECV LLFEPQDVQV QRFLIDRGTA DPDRKTIQLN
KLYTMMHYAR TEKCLLQYIV KYFGEADVPE CGKCSNCLDA SAMADVTEDA RKALSCVGRL
KGRFGISMAA KVLKGSREKR ILEFGFDRLS TYGLMRQWAE RDISDLLYYL VAEGYLRISD
GEYPTVSLTA EALPVLEGTV PVHRRQSAAA KRRDTGGTGL SAANAPLFDA LREWRRETAA
REKVPPFMLF FDAALREIAD RQPVTSEQLL GVKGIGAAKV SKYGHDVIAI VRKFKQEAGG
SSAGGAADED APMQPALFGA AATGGAGNGR GAGSNATVSG SAADAASEGE LARLEGMPSH
LQTLALYAEG KSLADIAGLR GMSRVTIENH LLRCGEEGEE LPWNEFIPER HEALIVETIG
RVGADKLKPI KEALPDEIDY FAIKAVIVKH RLSAAGE
//
