ID   A0A1I3PWM4_9BRAD        Unreviewed;       475 AA.
AC   A0A1I3PWM4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Membrane fusion protein, multidrug efflux system {ECO:0000313|EMBL:SFJ26234.1};
GN   ORFNames=SAMN05216525_12165 {ECO:0000313|EMBL:SFJ26234.1};
OS   Bradyrhizobium sp. Gha.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=1855318 {ECO:0000313|EMBL:SFJ26234.1, ECO:0000313|Proteomes:UP000199284};
RN   [1] {ECO:0000313|EMBL:SFJ26234.1, ECO:0000313|Proteomes:UP000199284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Gha {ECO:0000313|EMBL:SFJ26234.1,
RC   ECO:0000313|Proteomes:UP000199284};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
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DR   EMBL; FOQM01000021; SFJ26234.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3PWM4; -.
DR   STRING; 1855318.SAMN05216525_12165; -.
DR   OrthoDB; 9783047at2; -.
DR   Proteomes; UP000199284; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.420.20; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   NCBIfam; TIGR01730; RND_mfp; 1.
DR   PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR   PANTHER; PTHR30469:SF12; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          92..313
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
FT   REGION          394..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        422..447
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   475 AA;  50166 MW;  382763E8CADFFB88 CRC64;
     MLFKPDMKDN VKDGTAKKSR GRGFVMTLIT LAILGGLGYL GWSVMHQQPQ QQANGRGQQR
     PDLPVPVLAA TPKVQDVPVY LDGVGAIRAL NTVTVRSQVD GKLIVVNFTE GQDVKKGDVL
     AEIDPALYQA TYDQAVAKKA QDQAQLANQR IDLTRYEQLA ASNAGSKQQA DTQRAAVAQT
     EALVKADQAA IDNAAATLSY TKIVAPLSGR VGLRQVDQGN IIHASDTIGL VVITQLQPIA
     VWFSLPQQQI MRVNAAAAKG ALSVDVFGND GVTVIDTGKL TGIDNQVDQT TGTLKLKAEF
     PNANYQLWPG QFVNVRLKVE TLNQALVVPT SAVQRGPIGT FSYVIGEDNV VTAKPVTVTQ
     QNEHDAVIAS GLTANDKVVT TGFANLSDGS KVIIGRDEQT PSADLAPRKR TRAPQADGKG
     GQAKDGQKDG QGRDGEFRAK RKSSEGDQKG QTGPAPGPGA QPSGAQPSGS GAKQP
//