ID A0A1I3T277_9PSEU Unreviewed; 399 AA.
AC A0A1I3T277;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Vancomycin aglycone glucosyltransferase {ECO:0000313|EMBL:SFJ63637.1};
GN ORFNames=SAMN05421835_10744 {ECO:0000313|EMBL:SFJ63637.1};
OS Amycolatopsis sacchari.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=115433 {ECO:0000313|EMBL:SFJ63637.1, ECO:0000313|Proteomes:UP000199025};
RN [1] {ECO:0000313|EMBL:SFJ63637.1, ECO:0000313|Proteomes:UP000199025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44468 {ECO:0000313|EMBL:SFJ63637.1,
RC ECO:0000313|Proteomes:UP000199025};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Antibiotic biosynthesis; vancomycin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004660}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 28 family.
CC {ECO:0000256|ARBA:ARBA00006962}.
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DR EMBL; FORP01000007; SFJ63637.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3T277; -.
DR STRING; 115433.SAMN05421835_10744; -.
DR UniPathway; UPA00162; -.
DR Proteomes; UP000199025; Unassembled WGS sequence.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR GO; GO:0033072; P:vancomycin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR010610; EryCIII-like_C.
DR InterPro; IPR004276; GlycoTrans_28_N.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48050; STEROL 3-BETA-GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR48050:SF13; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF06722; EryCIII-like_C; 1.
DR Pfam; PF03033; Glyco_transf_28; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Reference proteome {ECO:0000313|Proteomes:UP000199025};
KW Transferase {ECO:0000313|EMBL:SFJ63637.1}.
FT DOMAIN 2..121
FT /note="Glycosyltransferase family 28 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03033"
FT DOMAIN 294..380
FT /note="Erythromycin biosynthesis protein CIII-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF06722"
SQ SEQUENCE 399 AA; 42307 MW; A604AA16A2A4519C CRC64;
MLLSTYGTRG DVEPLVALAV RLRELGAEVR ICTPPDEDFA PRPAEFGIPR VPVGSPVREL
MRETAPLSAA ELSRYRTKLV SAQFEALPVA AAGCDVLVAA GLAQVAARSV AEAAGISYVY
VAYSAVNLPS PHHAPPPRPG WPEPESDDNR TRWEMDARRV HAEFAETLNQ HRAALGLPPV
DDVRGHVYSG RPWLAADPVL GPWRETAGLD VVQTGAWTLP DERPLPAELV AFLDAGAAPV
YVGFGSMRPS PDIGHRAVEA IRAQGHRVLV SRGWADLDLV DGREDLFAIG EVNQQRLFPR
VAAVVHHGGA GTTLVAARAG VPQVVIPLPV ADNPYWADRI ADLGVGVALH GGAPASAALY
AAIETALAPE TRARAKALAA RVGTDGAMLA ARRLLGSRQ
//
