ID A0A1I3T4I5_9RHOB Unreviewed; 452 AA.
AC A0A1I3T4I5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Mechanosensitive ion channel {ECO:0000313|EMBL:SFJ65964.1};
GN ORFNames=SAMN04488095_3294 {ECO:0000313|EMBL:SFJ65964.1};
OS Jannaschia pohangensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia.
OX NCBI_TaxID=390807 {ECO:0000313|EMBL:SFJ65964.1, ECO:0000313|Proteomes:UP000199110};
RN [1] {ECO:0000313|EMBL:SFJ65964.1, ECO:0000313|Proteomes:UP000199110}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19073 {ECO:0000313|EMBL:SFJ65964.1,
RC ECO:0000313|Proteomes:UP000199110};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; FORA01000005; SFJ65964.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3T4I5; -.
DR STRING; 390807.SAMN04488095_3294; -.
DR OrthoDB; 9799209at2; -.
DR Proteomes; UP000199110; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199110};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 266..332
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 340..423
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 452 AA; 49949 MW; AB5F9F726F84FDE8 CRC64;
MEEDILEAIP LKDELLRIWG NVTGFTSDLL QPGWKLWQVL IVLAIMVIAL LLRRWAADRM
TAWMRGQTGR PKWQLRALVI VRNRLGLIIF ALLAWAVFIA MREMTWPSRS YLVGLSATIA
NAWVVVAFVS RLVKNPFLRK IVTWGLWGYV TLFYLGILEE TKAALEAAAI QFGEFRLSIL
GVLTALVAIG IFFAVARFLA VTTTARISKV EDISPSMRVL MVKLLQIILY AGAFFLGLKA
VGFDLTGLAV LSGAIGVGLG FGLQKVVSNL VSGVIILLDK SIKPGDVISV GDTFGWINSL
TARYVSITTR DGKEYLVPNE DLITGLVVNW SHTNQLVRLD IYFGTAYSDD PHVVRRVAIE
AALATERVLS IKAPVCHIVG FGDSSVDYIL RFWINDPTDG LTNIRGNVYL ALWDAFRENG
ISIPFPQREV RMLGDAPFHP DEAGEASSKS PG
//
