ID A0A1I3TKR2_9FLAO Unreviewed; 313 AA.
AC A0A1I3TKR2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 9.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SFJ71465.1};
GN ORFNames=SAMN04487893_11411 {ECO:0000313|EMBL:SFJ71465.1};
OS Myroides guanonis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Myroides.
OX NCBI_TaxID=1150112 {ECO:0000313|EMBL:SFJ71465.1, ECO:0000313|Proteomes:UP000243887};
RN [1] {ECO:0000313|Proteomes:UP000243887}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26542 {ECO:0000313|Proteomes:UP000243887};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FORU01000014; SFJ71465.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3TKR2; -.
DR STRING; 1150112.SAMN04487893_11411; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000243887; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd12179; 2-Hacid_dh_14; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43026; 2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED; 1.
DR PANTHER; PTHR43026:SF1; 2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000243887}.
FT DOMAIN 30..310
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 106..290
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 313 AA; 35398 MW; 583985FCF78A3628 CRC64;
MKKVLHIDSN HPIMLSGLEA LGYTNVENYI STKEEIEKSI SDYEGIVIRS RFKIDQEFIK
KATNLKFIAR VGAGLENIDC EYAMSKGIAL IAAPEGNRTA VGEHALGMLL CLMNRLNLVD
QEVRNGVWLR EENRGFEIEG KTVGIIGYGN MGKAFAKRLQ GFDCEVLFYD IKPNVEDDFA
KQVSLRELQR RTDILSLHTP QTPETLYLIN KDIIEGFQKP IWFINTARGK SVNTADLVEA
LKSEKVRGAA LDVLEYEKNS FEDMFTEGTL PEPMNYLINA PNVLLSPHIA GWTWESKEKL
AQTILDKLKR ITL
//
