ID   A0A1I3TSH1_9BURK        Unreviewed;       106 AA.
AC   A0A1I3TSH1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Guanidinium exporter {ECO:0000256|ARBA:ARBA00039168};
GN   ORFNames=SAMN05192543_11094 {ECO:0000313|EMBL:SFJ73570.1};
OS   Paraburkholderia megapolitana.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=420953 {ECO:0000313|EMBL:SFJ73570.1, ECO:0000313|Proteomes:UP000199548};
RN   [1] {ECO:0000313|EMBL:SFJ73570.1, ECO:0000313|Proteomes:UP000199548}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 23650 {ECO:0000313|EMBL:SFJ73570.1,
RC   ECO:0000313|Proteomes:UP000199548};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC       Gdx/SugE subfamily. {ECO:0000256|ARBA:ARBA00038151}.
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DR   EMBL; FOQU01000010; SFJ73570.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3TSH1; -.
DR   STRING; 420953.SAMN05192543_11094; -.
DR   OrthoDB; 9808638at2; -.
DR   Proteomes; UP000199548; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   PANTHER; PTHR30561:SF0; GUANIDINIUM EXPORTER; 1.
DR   PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199548};
KW   Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   106 AA;  11067 MW;  7028625582DE1E62 CRC64;
     MSWVLLFIAG LLEVAWAAGL KTSEGFTRLW PSVFTIVTAL GSFILLAMAM RQLPLGTAYA
     VWTGIGAVGA FVFGIVMMGE AVTLARVASA VLIVIGLIGL KLSSGH
//