ID   A0A1I3V1T0_9BACL        Unreviewed;       339 AA.
AC   A0A1I3V1T0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=4-hydroxythreonine-4-phosphate dehydrogenase {ECO:0000313|EMBL:SFJ88919.1};
GN   ORFNames=SAMN05421852_13113 {ECO:0000313|EMBL:SFJ88919.1};
OS   Thermoflavimicrobium dichotomicum.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC   Thermoflavimicrobium.
OX   NCBI_TaxID=46223 {ECO:0000313|EMBL:SFJ88919.1, ECO:0000313|Proteomes:UP000199545};
RN   [1] {ECO:0000313|EMBL:SFJ88919.1, ECO:0000313|Proteomes:UP000199545}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44778 {ECO:0000313|EMBL:SFJ88919.1,
RC   ECO:0000313|Proteomes:UP000199545};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000256|ARBA:ARBA00001968};
CC   -!- SIMILARITY: Belongs to the PdxA family. PdxA2 subfamily.
CC       {ECO:0000256|ARBA:ARBA00009464}.
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DR   EMBL; FORR01000031; SFJ88919.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3V1T0; -.
DR   STRING; 46223.SAMN05421852_13113; -.
DR   OrthoDB; 9801783at2; -.
DR   Proteomes; UP000199545; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR005255; PdxA_fam.
DR   NCBIfam; TIGR00557; pdxA; 1.
DR   PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR30004:SF6; D-THREONATE 4-PHOSPHATE DEHYDROGENASE; 1.
DR   Pfam; PF04166; PdxA; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199545}.
SQ   SEQUENCE   339 AA;  37256 MW;  27AA86296D285138 CRC64;
     MSRPIIGITI GDPAGIGPEI TLKALQKEEF YRISKPLVIG SYPVMKKVSE QLGISVQFNR
     IERVQDGTYE YGTIDVLDLN NVDVDRLEMG KVQKECGQAS FEYIRKSAEL ALKGEIDAVC
     TAPINKEALK AANVPYIGHT EMFADLTKAE REMTMFSIEN VKIFFLTRHV SLAEACRQIN
     NKDFVLRGIR QAYQALEDLI GQKPRLAVAG LNPHSGEGGL LGREEIDAIR PAVEQACEEG
     MDVVGPVPAD SVFHFARKGH YDAVLSLYHD QGHIAAKMID FEKTVSITLG LPILRTSVDH
     GTAFDIAGKG IASPVSMIEA YKAAVQYAGR YPKKKTAVM
//