ID A0A1I3W0I9_9RHOB Unreviewed; 561 AA.
AC A0A1I3W0I9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Chloride channel protein, CIC family {ECO:0000313|EMBL:SFK01124.1};
GN ORFNames=SAMN04488138_11944 {ECO:0000313|EMBL:SFK01124.1};
OS Celeribacter halophilus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Celeribacter.
OX NCBI_TaxID=576117 {ECO:0000313|EMBL:SFK01124.1, ECO:0000313|Proteomes:UP000183299};
RN [1] {ECO:0000313|EMBL:SFK01124.1, ECO:0000313|Proteomes:UP000183299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.8891 {ECO:0000313|EMBL:SFK01124.1,
RC ECO:0000313|Proteomes:UP000183299};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FORY01000019; SFK01124.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3W0I9; -.
DR STRING; 576117.SAMN04488138_11944; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000183299; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000183299};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 494..554
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 561 AA; 59413 MW; EDC8DEA3C58F2E24 CRC64;
MAEEKTSYPA KAMAEIREGL SDALDLVRRR GPSQIQFWFI ALLIGIASGF AALGFRKGID
LLQGMFYGTP DLRHLHTFAS DLPWYWVLFL PVFGGLVVGI VLNWFTPDGR VRSVADVIEG
AALNQGRVEK RAGLASAFAS LITLSTGGSS GREGPVVHLA GVISTWVSNR LHADGITGRD
LLGCAVAAAV SASFNAPIAG ALFALEVVLR HFAVHAFAPI VIASAAGTVI NRLEFGGVTE
FTLAAEGALS FYVELPAFLI LGLLSGLVAV LMMRSIFMAD DFGSWVQEKL HLPPVLRPAF
AGLLLGLMAI QFPHIIGVGY ETTSAALTGH LLLWQAVVYT VIKVIAVSIT MAGRMGGGVF
SPALMVGALT GLSFGLVATA IFPTVSGTAT LYALAGMGAV AAAVLGAPIS TTLIVFELTG
DWQTGLAVMV AVSLSTALAS RLVDRSFFLT LLERRGVHLA AGPQAYLLAT VRVHQCYRAP
DAPRAAPEAA CRELISQGIY LSPNATLERA MPLFEKNNLI FIPVVTLREE TGPELHGALF
HVDALRVFSR KLAETAAEEH S
//
