ID   A0A1I3WSX2_HALDA        Unreviewed;       446 AA.
AC   A0A1I3WSX2;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SFK10293.1};
GN   ORFNames=SAMN04487936_107116 {ECO:0000313|EMBL:SFK10293.1};
OS   Halobacillus dabanensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX   NCBI_TaxID=240302 {ECO:0000313|EMBL:SFK10293.1, ECO:0000313|Proteomes:UP000183557};
RN   [1] {ECO:0000313|EMBL:SFK10293.1, ECO:0000313|Proteomes:UP000183557}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.3704 {ECO:0000313|EMBL:SFK10293.1,
RC   ECO:0000313|Proteomes:UP000183557};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FOSB01000007; SFK10293.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3WSX2; -.
DR   STRING; 240302.BN982_00716; -.
DR   Proteomes; UP000183557; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF14; SODIUM_AMINO ACID (ALANINE) SYMPORTER-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        14..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        96..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        185..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        241..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        303..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        351..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        394..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        417..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   446 AA;  47855 MW;  2026307468C9BDD2 CRC64;
     MEQLTNVFIE INSFLWGPVM LIFLLGTGVW LTFQLRFIQV RSLGRGFKLT FAPLFKKEKT
     EGIHSFKALA TSISAQVGTG NLAGVATAIA AGGPGAIFWM WISSFFGMAT IFAEAVLAQL
     YKVKKGDEVH GGPAYYIRDG LGSKWLAGFF SIAIILALGF VGNMVQSNAI TTAMNETIGS
     SSMALNLGIG GVIAFFIGLI LFGGIGRIST FAGNVVPIMA LLYIIGSLII MFNYWEQVLP
     TFQLIIQAAI SPEAAGGGVL GATIKEAIRY GIARGLFSNE AGMGSTPHAH AIANVKRPSH
     QGLVAMVGVF IDTVVICTLT AMVILLTDAH QAGLQGSAIT QEGFARGLGD FGIPFIAICL
     LFFAFTTILG WAYFGEVNVK FLFGEKGVPF YRGIVLLFIV LGSLVQVDFV WEMADTFNAL
     MVVPNLVAIL ALTKMIKSTW RQDELL
//