ID A0A1I3Y7I6_9PROT Unreviewed; 713 AA.
AC A0A1I3Y7I6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase {ECO:0000313|EMBL:SFK27785.1};
GN ORFNames=SAMN05216302_100366 {ECO:0000313|EMBL:SFK27785.1};
OS Nitrosomonas aestuarii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=52441 {ECO:0000313|EMBL:SFK27785.1, ECO:0000313|Proteomes:UP000199533};
RN [1] {ECO:0000313|Proteomes:UP000199533}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nm69 {ECO:0000313|Proteomes:UP000199533};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
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DR EMBL; FOSP01000003; SFK27785.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I3Y7I6; -.
DR STRING; 52441.SAMN05216302_100366; -.
DR OrthoDB; 8828485at2; -.
DR Proteomes; UP000199533; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:UniProt.
DR CDD; cd09140; PLDc_vPLD1_2_like_bac_1; 1.
DR CDD; cd09143; PLDc_vPLD1_2_like_bac_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR18896:SF76; PHOSPHOLIPASE; 1.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR Pfam; PF00614; PLDc; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199533};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 488..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 127..154
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 350..372
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 713 AA; 79864 MW; D699F0C364E6D899 CRC64;
MSSLLQTDKN CWRIENADRA SFLIDGADYF AALREAMKNA QHAIYILGWD INSQLEMVRN
NEDDGYPNQL GAFLNALAQQ KQHLNVYILN WDFAMLYAPS REWLPIYQFD WKTHSRVQFC
LDDHLPSGAS HHQKMVIIDD ALAFIGGLDL TMGRWDTSDH LHDNPRRDRI DDKIARPFHD
VQVMLEGDVA FALAELARER WQVATTKTLQ PVDRKQPSEL WPSAVSADMK NVAVGLARTR
CAYEQLTEVR EIQQFYLDAI QSAKHYIYIE NQYFTVPSIA EAFQNSLKKE QGPEIVIVQP
KATDGWMSQL TMDVLRTRLI KQLQQNDRYK RLKAFYPDGP GLSENPINVH AKIMIVDDTL
VTVGSANLNN RSMGLDIECN IAIDATSDDA LQQSIAGFHH RLLAEHLAST PEDVQKTLHE
TNSLIAGIEK LTQTDDRHLT VLPLDLEPEI DRMVPDADIT DPKEPLEPEF FMSRILPEKS
MKSIKSRIIS WLVMIAGIAA LVAIWKWTPL QGWAYIQSAS SALAEFHKTP ALPVWIVMGF
MLAGFVRFPI SLLVIPAVFL LGLLQGFIVS IVGGVLSAFT VYVIGKKLDR NTIRKLAGSQ
LNLISNKLAQ RGIISIVAMR IVPAAPFTLI NLVAGASHFH FRDYFVGTIL GMAPGLFAVS
VITSLALAAI DSPATENLIW LAFAVTVAMS AAYILMSWIA GKAGYRNKTS KKK
//
