ID   A0A1I3YBV6_9PROT        Unreviewed;      1141 AA.
AC   A0A1I3YBV6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Cholesterol oxidase {ECO:0000313|EMBL:SFK29285.1};
GN   ORFNames=SAMN05216302_1003126 {ECO:0000313|EMBL:SFK29285.1};
OS   Nitrosomonas aestuarii.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=52441 {ECO:0000313|EMBL:SFK29285.1, ECO:0000313|Proteomes:UP000199533};
RN   [1] {ECO:0000313|Proteomes:UP000199533}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nm69 {ECO:0000313|Proteomes:UP000199533};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOSP01000003; SFK29285.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3YBV6; -.
DR   STRING; 52441.SAMN05216302_1003126; -.
DR   OrthoDB; 9787779at2; -.
DR   Proteomes; UP000199533; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR   PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199533}.
FT   DOMAIN          83..295
FT                   /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00732"
FT   DOMAIN          489..555
FT                   /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05199"
SQ   SEQUENCE   1141 AA;  124896 MW;  96335365D8CD4531 CRC64;
     MKRLASPRTR LKDRYDAIVI GSGYGGAIAA SRLGRMKRGD GSKLDVCLLE RGREIQTGEY
     PDTLLEAGKE FQINLHDKHI GDHTGLFNLY AGKDMNVIVG CGLGGTSLIN ANVSLKADDR
     VFDDPCWPDE IRQDRERMSV CYDRAMTMLG AQPFPDGQHG VPTLPKAEAQ KNSAKAVNRP
     VTFPPINVTF KDRINEAGVH QPACTYCGDC VSGCNYGAKN TTLMNYLPDA WNNGVEIYTQ
     IAVRWLEKDG SDWLVHCQIM EVGREIFDAP DLVLRCKQVF LGAGTLGSTE ILLRSKENGL
     PLSDKVGEHF SSNGDVLGFG FNNDMPINAI GFGNHPVGEI DPVGPCITTM IDDRATADLE
     QGLILEEGSL PGALSSILPG LMASAAGLIG KDTDSGLNDE ISEHGRVLDS MVRGAYHGAV
     HNTQVYLIMS HDGSDGRLTM HNNCISVDWP DVGDKPVFKR DNDFMEQVTA ANGGTYVQNP
     IWTKELDNSL VTVHPLGGCC MGKDAQSGVV DHRGRVFTGA AGTTVHEGLH VADGSIVPRS
     LGVNPLLTIS ALTERSMELF AEAEGYTYDF TSLSQPREAE PATVGVRFTE TMRGWWAEHG
     DYEQAVRSGK EGGNSLDFTL TVSVNDLDAL IKQGGGYNGG MVGTVTAPGL SASPLTVTQG
     VFNLFARDPK QVGQEYMKYR FQMYAEDGKT WYFEGHKIIH NDPGIDIWSD TTQLYITLYD
     GADAAAVKGR GMLYIQPLDF VRQITTIDAI GALTMTDRLQ AIARFGIYFA GDLYHIYGGV
     LVPPQYLDAD APPRKKRSLR VGAPEVYHFN TSDGVPLRLT RYQGGKKGPL LMVHGAGVSS
     QIFTTDTIDT NLLEYLYING YDCWLLEMRI SIALSSAKQG WTLDDIARYD YPAAVKIILD
     ATGSPDIQAL VHCAGSTTFF MAMMSGLQHV RAAVASQIGP DHIVAPIVKA KAGLHLPSLL
     DAIGVDSATA YADNKSSWLN KLYDKALNLQ HFDVEERCAS AVCHRVSFMY SLLYEHDQLN
     RLTHDNLHEL FGICHMDIFR HLALCAREKH IVNAEGKNVY TPHWDKLKIP ITFIHGVENA
     SYLPESTERS FSKLVEVNGP DGYARHVIPG YGHIDCIFGK NAVKDVYPYM LSALDQTNQA
     V
//