ID   A0A1I3YC56_9CELL        Unreviewed;       483 AA.
AC   A0A1I3YC56;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SFK28861.1};
GN   ORFNames=SAMN05216467_2696 {ECO:0000313|EMBL:SFK28861.1};
OS   Cellulomonas sp. KH9.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Cellulomonadaceae;
OC   Cellulomonas.
OX   NCBI_TaxID=1855324 {ECO:0000313|EMBL:SFK28861.1, ECO:0000313|Proteomes:UP000199404};
RN   [1] {ECO:0000313|Proteomes:UP000199404}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KH9 {ECO:0000313|Proteomes:UP000199404};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FOSE01000004; SFK28861.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3YC56; -.
DR   STRING; 1855324.SAMN05216467_2696; -.
DR   OrthoDB; 9806926at2; -.
DR   Proteomes; UP000199404; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199404};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        18..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        57..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        139..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        180..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        208..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        239..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        302..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        350..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        394..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        419..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   483 AA;  49728 MW;  DDF154D386695B27 CRC64;
     MDLQVGIDWL TDALYSSWLV YLLVGVGLWF SVRTGFVQVR MFPAMVRQLF ASRTGSAGGI
     SSFQAFAVGL ASRVGTGNIA GVAVALTLGG PGAVFWMWLV AAVGMATALV EATLAQVFKV
     RQPDGSYRGG PAYYIQRGLG SYRWGAVFAV LLVVTFGFAF NMVQANTIAD TLASNHQLPA
     PWTAVGLMVV AAPVLFGGVR RVARVAEVVV PLMAGLYLLL AVVVVALNIS TLPDVFRQIL
     QGAFGLDSAL AGTGGGILAA VLNGTKRGLF SNEAGMGSVP NTAATATVSH PVKQGLVQSL
     GVFVDTMLVC SATAFVVLSA GPAVYVPGQT GASAGAALTS DAVTHELGDW AALPMTVLIF
     TFAFSSVLGN YAYAEVNLTF LGVHGRALTA LRTLVLAAVG IGSLLTLTTV WALADIAMAF
     MATVNLVAIV LLSRWALGAL ADYGAARRAG GDDRFVGEGN PLLPGDVPGD VWAAGVRDGA
     PAG
//