ID   A0A1I3Z7N4_9ACTN        Unreviewed;       341 AA.
AC   A0A1I3Z7N4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Predicted naringenin-chalcone synthase {ECO:0000313|EMBL:SFK39681.1};
GN   ORFNames=SAMN04488085_101385 {ECO:0000313|EMBL:SFK39681.1};
OS   Geodermatophilus ruber.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Geodermatophilus.
OX   NCBI_TaxID=504800 {ECO:0000313|EMBL:SFK39681.1, ECO:0000313|Proteomes:UP000199152};
RN   [1] {ECO:0000313|EMBL:SFK39681.1, ECO:0000313|Proteomes:UP000199152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45317 {ECO:0000313|EMBL:SFK39681.1,
RC   ECO:0000313|Proteomes:UP000199152};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR   EMBL; FOSW01000001; SFK39681.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I3Z7N4; -.
DR   STRING; 504800.SAMN04488085_101385; -.
DR   InParanoid; A0A1I3Z7N4; -.
DR   Proteomes; UP000199152; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199152}.
FT   DOMAIN          65..195
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          216..337
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        137
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   341 AA;  35259 MW;  A61B464054AE4194 CRC64;
     MNAVVTGAGS ALPAALDQDD LWEGFFAGHY AGVRAARRIF AASGVRRRHA VANPIDEDIS
     GWGTAARMQR YLQEALPLGK QAVAAALDDA GLAPGDVGLF AVATCTGYAT PGLDIRLAGD
     LGMPPGLQRL LVGHMGCYAA IPGLAAAGDY VTARSRPAVL LCCELTSLHV QPAQADLEQV
     VAHALFSDAA AAVVLQPGAG RGRRLADVVV RTDASTADHM TWDVTDLGFR MGLSPRVPDV
     LARHVGEVVD ELLTGAGLRT GDVAGWAVHP GGPRILDVVR DELGLAEQQL AASRHVLAEH
     GNCSSATVLL VLEELADVDG PVVAMAFGPG LTLYAALLLP A
//